Association between clot composition and stroke origin in mechanical thrombectomy patients: analysis of the Stroke Thromboembolism Registry of Imaging and …

…, L Pisani, GM Rodrigues, IC Thacker… - Journal of …, 2021 - jnis.bmj.com
Background We retrospectively evaluated the composition of retrieved clots from ischemic
stroke patients to study the association between histological composition and stroke etiology …

Platelet-rich emboli in cerebral large vessel occlusion are associated with a large artery atherosclerosis source

…, A Douglas, R Kadirvel, KF Layton, IC Thacker… - Stroke, 2019 - Am Heart Assoc
Background and Purpose— Nearly 30% of large vessel occlusion acute ischemic stroke
clots are from an unknown source. We assessed histological clot composition in a series of …

Platelet-rich clots as identified by Martius Scarlet Blue staining are isodense on NCCT

…, J Chueh, AS Puri, KF Layton, IC Thacker… - Journal of …, 2019 - jnis.bmj.com
Background Current studies on clot characterization in acute ischemic stroke focus on fibrin
and red blood cell composition. Few studies have examined platelet composition in acute …

Histological evaluation of acute ischemic stroke thrombi may indicate the occurrence of vessel wall injury during mechanical thrombectomy

…, J Soomro, AM Demchuk, IC Thacker… - Journal of …, 2022 - jnis.bmj.com
Background Several animal studies have demonstrated that mechanical thrombectomy (MT)
for acute ischemic stroke (AIS) may cause vessel wall injury (VWI). However, the …

Quantification of clot spatial heterogeneity and its impact on thrombectomy

…, L Pisani, GM Rodrigues, IC Thacker… - Journal of …, 2022 - jnis.bmj.com
Background Compositional and structural features of retrieved clots by thrombectomy can
provide insight into improving the endovascular treatment of ischemic stroke. Currently, …

Per pass analysis of thrombus composition retrieved by mechanical thrombectomy

…, HJ Cloft, Y Liu, IC Thacker… - Interventional …, 2021 - journals.sagepub.com
Background and aim Mechanical thrombectomy (MT) for large vessel occlusion often requires
multiple passes to retrieve the entire thrombus load. In this multi-institutional study we …

Histological composition of retrieved emboli in acute ischemic stroke is independent of pre-thrombectomy alteplase use

…, L Pisani, G Rodrigues, IC Thacker… - Journal of Stroke and …, 2022 - Elsevier
Background and purpose Given recent evidence suggesting the clot composition may be
associated with revascularization outcomes and stroke etiology, clot composition research has …

Clot composition and recanalization outcomes in mechanical thrombectomy

…, K Doyle, LE Savastano, HJ Cloft, IC Thacker… - Journal of …, 2023 - jnis.bmj.com
Background Mechanical thrombectomy (MT) has become standard for large vessel
occlusions, but rates of complete recanalization are suboptimal. Previous reports correlated …

Multidisciplinary treatment of a large cerebral dural arteriovenous fistula using embolization, surgery, and radiosurgery

CA Giller, DW Barnett, IC Thacker, JH Hise… - Baylor University …, 2008 - Taylor & Francis
Dural arteriovenous fistulae are rare lesions composed of abnormal connections between
meningeal arteries and the dural sinuses or leptomeningeal veins. Treatment is challenging …

Correlation of von Willebrand factor and platelets with acute ischemic stroke etiology and revascularization outcome: an immunohistochemical study

…, J Soomro, AM Demchuk, IC Thacker… - Journal of …, 2023 - jnis.bmj.com
Background Platelets and von Willebrand factor (vWF) are key components of acute ischemic
stroke (AIS) emboli. We aimed to investigate the CD42b (platelets)/vWF expression, its …