Compensatory cortical activation observed by fMRI during a cognitive task at the earliest stage of multiple sclerosis

…, JP Ranjeva, S Confort‐Gouny, I Malikova… - Human brain …, 2003 - Wiley Online Library
Recent functional magnetic resonance imaging (fMRI) studies have suggested that functional
cortical changes seen in patients with early relapsing‐remitting multiple sclerosis (MS) can …

Early cognitive impairment in patients with clinically isolated syndrome suggestive of multiple sclerosis

…, F Reuter, B Audoin, I Malikova… - Multiple Sclerosis …, 2007 - journals.sagepub.com
Cognitive impairment in patients with multiple sclerosis (MS) is a common occurrence and is
generally fairly circumscribed. The prevalence of the cognitive deficits usually encountered …

Magnetic resonance study of the influence of tissue damage and cortical reorganization on PASAT performance at the earliest stage of multiple sclerosis

…, JP Ranjeva, D Ibarrola, I Malikova… - Human brain …, 2005 - Wiley Online Library
We sought to determine the influence of tissue damage and the potential impact of cortical
reorganization on the performance to the Paced Auditory Serial Addition Test (PASAT) in …

Atrophy mainly affects the limbic system and the deep grey matter at the first stage of multiple sclerosis

…, W Zaaraoui, F Reuter, A Rico, I Malikova… - Journal of Neurology …, 2010 - jnnp.bmj.com
Background The existence of grey matter (GM) atrophy right after the first clinical event
suggestive of multiple sclerosis (MS) remains controversial. The aim of this study was therefore to …

Assessing brain connectivity at rest is clinically relevant in early multiple sclerosis

…, D Wybrecht, E Soulier, I Malikova… - Multiple Sclerosis …, 2012 - journals.sagepub.com
Objective: The present study aims to determine the clinical counterpart of brain resting-state
networks reorganization recently evidenced in early multiple sclerosis. Methods: Thirteen …

Acute fulminant demyelinating disease: a descriptive study of 60 patients

…, P Cabre, J Pelletier, I Malikova… - Archives of …, 2007 - jamanetwork.com
Background Acute demyelinating encephalomyelitis (ADEM) is characterized by a severe
inflammatory attack, frequently secondary to infectious events or vaccinations. To date, no …

Distribution of Brain Sodium Accumulation Correlates with Disability in Multiple Sclerosis: A Cross-sectional 23Na MR Imaging Study

…, S Konstandin, B Audoin, AM Nagel, A Rico, I Malikova… - Radiology, 2012 - pubs.rsna.org
Purpose To quantify brain sodium accumulations and characterize for the first time the spatial
location of sodium abnormalities at different stages of relapsing-remitting (RR) multiple …

Structure of WM bundles constituting the working memory system in early multiple sclerosis: a quantitative DTI tractography study

…, F Reuter, MVA Duong, S Confort-Gouny, I Malikova… - Neuroimage, 2007 - Elsevier
Working memory impairment is frequently observed in patients with early multiple sclerosis (MS).
MRI and functional MRI studies have shown that working memory impairment is mostly …

Frequency of cognitive impairment dramatically increases during the first 5 years of multiple sclerosis

…, L Crespy, A Faivre, A Rico, I Malikova… - Journal of Neurology …, 2011 - jnnp.bmj.com
Previous studies have demonstrated that cognitive impairment is already present in patients
suffering from a clinically isolated syndrome (CIS) suggestive of multiple sclerosis (MS). …

Modulation of effective connectivity inside the working memory network in patients at the earliest stage of multiple sclerosis

…, B Audoin, S Treseras, D Ibarrola, I Malikova… - Neuroimage, 2005 - Elsevier
fMRI and structural equation modeling (SEM) were used to study effective connectivity
inside the working memory network in patients at the earliest stage of multiple sclerosis (MS), …