Tuberous sclerosis (TSC) is a relatively common hamartoma syndrome caused by mutations
in either of two genes, TSC1 and TSC2. Here we report comprehensive mutation analysis …

Background Although environmental lead exposure is associated with significant deficits in
cognition, executive functions, social behaviors, and motor abilities, the neuroanatomical …

Childhood lead exposure is associated with adverse cognitive, neurobehavioral and motor
outcomes, suggesting altered brain structure and function. The purpose of this work was to …

PURPOSE To evaluate the frequency and nature of spinal pathology, the frequency of
clinically silent lesions, and the potential benefit of screening spinal MR in neurofibromatosis …

OBJECTIVES. The purpose of this work was to assess the long-term impact of childhood lead
exposure on the neurosubstrate of language function and brain organization. METHODS. …

Twenty-nine patients with TS who are regularly followed in the multidisciplinary TS Clinic at
the Children’s Hospital Medical Center in Cincinnati participated in the study. This group of …

Objective —To estimate heritabilities and genetic correlations among 4 traits of hip joints (distraction
index [DI], dorsolateral subluxation [DLS] score, Norberg angle [NA], and extended–…

This study characterized structural abnormalities associated with onset of seizures in children,
using magnetic resonance imaging and a standardized classification system in a large …

This study investigates the morphometry of Heschl's gyrus and its included primary auditory
cortex (PAC) in hearing impaired (HI) and normal hearing (NH) infants. Fourty-two infants, …

Background Childhood lead exposure adversely affects neurodevelopment. However, few
studies have examined changes in human brain metabolism that may underlie known …