User profiles for J Hernesniemi

Juha Hernesniemi

- Verified email at hus.fi - Cited by 25146

Jussi Hernesniemi

- Verified email at uta.fi - Cited by 4250

Saccular intracranial aneurysm: pathology and mechanisms

…, M Korja, A Laakso, M Niemelä, J Hernesniemi - Acta …, 2012 - Springer
Saccular intracranial aneurysms (sIA) are pouch-like pathological dilatations of intracranial
arteries that develop when the cerebral artery wall becomes too weak to resist hemodynamic …

Inflammatory changes in the aneurysm wall: a review

R Tulamo, J Frösen, J Hernesniemi… - Journal of …, 2018 - jnis.bmj.com
Rupture of a saccular intracranial artery aneurysm (IA) causes subarachnoid hemorrhage, a
significant cause of stroke and death. The current treatment options, endovascular coiling …

Microneurosurgical management of anterior communicating artery aneurysms

J Hernesniemi, R Dashti, M Lehecka, M Niemelä… - Surgical neurology, 2008 - Elsevier
BACKGROUND: Anterior communicating artery complex is the most frequent site of intracranial
aneurysms in most reported series. Anterior communicating artery aneurysms are the …

The same sequence variant on 9p21 associates with myocardial infarction, abdominal aortic aneurysm and intracranial aneurysm

…, RE Ferrell, S Sveinbjornsdottir, J Hernesniemi… - Nature …, 2008 - nature.com
Recently, two common sequence variants on 9p21, tagged by rs10757278-G and rs10811661-T,
were reported to be associated with coronary artery disease (CAD) 1, 2, 3, 4 and type 2 …

Remodeling of saccular cerebral artery aneurysm wall is associated with rupture: histological analysis of 24 unruptured and 42 ruptured cases

…, M Niemelä, J Hernesniemi, J Jääskeläinen - Stroke, 2004 - Am Heart Assoc
Background and Purpose— The cellular mechanisms of degeneration and repair preceding
rupture of the saccular cerebral artery aneurysm wall need to be elucidated for rational …

Multi-ethnic genome-wide association study for atrial fibrillation

…, TB Harris, C Hayward, SR Heckbert, J Hernesniemi… - Nature …, 2018 - nature.com
Atrial fibrillation (AF) affects more than 33 million individuals worldwide 1 and has a complex
heritability 2 . We conducted the largest meta-analysis of genome-wide association studies (…

Rare and low-frequency coding variants alter human adult height

…, IM Heid, K Heikkilä, Ø Helgeland, J Hernesniemi… - Nature, 2017 - nature.com
Height is a highly heritable, classic polygenic trait with approximately 700 common associated
variants identified through genome-wide association studies so far. Here, we report 83 …

Natural history of brain arteriovenous malformations: a long-term follow-up study of risk of hemorrhage in 238 patients

JA Hernesniemi, R Dashti, S Juvela, K Väärt… - …, 2008 - journals.lww.com
OBJECTIVE: Long-term follow-up studies in patients with brain arteriovenous malformations
(AVM) have yielded contradictory results regarding both risk factors for rupture and annual …

Outcomes of early endovascular versus surgical treatment of ruptured cerebral aneurysms: a prospective randomized study

…, R Vanninen, H Hurskainen, T Saari, J Hernesniemi… - Stroke, 2000 - Am Heart Assoc
… 42 Drake CG, Peerless SJ, Hernesniemi JA. Complications of surgery for vertebrobasilar
artery aneurysms and final comments. In: Surgery of Vertebrobasilar Aneurysms: London, …

Genome-wide association study of intracranial aneurysm identifies three new risk loci

…, D Rüfenacht, JE Jääskeläinen, J Hernesniemi… - Nature …, 2010 - nature.com
Saccular intracranial aneurysms are balloon-like dilations of the intracranial arterial wall;
their hemorrhage commonly results in severe neurologic impairment and death. We report a …