Mitochondria play important roles in cellular energy metabolism, free radical generation, and
apoptosis. Defects in mitochondrial function have long been suspected to contribute to the …

Histone deacetylases (HDACs) play an important role in the epigenetic regulation of gene
expression by catalyzing the removal of acetyl groups, stimulating chromatin condensation …

Heat-shock proteins (HSPs) are molecular chaperones that regulate protein folding to
ensure correct conformation and translocation and to avoid protein aggregation. Heat-shock …

BACKGROUND AND PURPOSE: In subjects performing no specific cognitive task (“resting
state”), time courses of voxels within functionally connected regions of the brain have high …

Cancer cells generally exhibit increased glycolysis for ATP generation (the Warburg effect)
due in part to mitochondrial respiration injury and hypoxia, which are frequently associated …

This paper describes an experiment germane to the teaching of media literacy. It gives a
quantitative account of interracial behavior, using a methodology which could be used in the …

BACKGROUND AND PURPOSE: Disruption of the cytoskeletal network and axonal membranes
characterizes diffuse axonal injury (DAI) in the first few hours after traumatic brain injury. …

Cancer cells are under intrinsic increased oxidative stress and vulnerable to free radical-induced
apoptosis. Here, we report a strategy to hinder mitochondrial electron transport and …

Novel therapeutic strategies are needed to address the emerging problem of imatinib resistance.
The histone deacetylase (HDAC) inhibitor suberoylanilide hydroxamic acid (SAHA) is …

Cancer cells exhibit increased glycolysis for ATP production due, in part, to respiration
injury (the Warburg effect). Because ATP generation through glycolysis is less efficient than …