The 2010 McDonald criteria for the diagnosis of multiple sclerosis are widely used in research
and clinical practice. Scientific advances in the past 7 years suggest that they might no …

During the past decades, better understanding of relapsing-remitting multiple sclerosis
disease mechanisms have led to the development of several disease-modifying therapies, …

Traditionally, multiple sclerosis has been categorised by distinct clinical descriptors—relapsing-remitting,
secondary progressive, and primary progressive—for patient care, research, …

Background No treatment has consistently shown efficacy in slowing disability progression
in patients with secondary progressive multiple sclerosis (SPMS). We assessed the effect of …

Regulated glycosylation controls T cell processes, including activation, differentiation and
homing by creating or masking ligands for endogenous lectins. Here we show that stimuli …

Although Vitamin D is best known as a modulator of calcium homeostasis, it also has immune
modulating potential. A protective effect of Vitamin D on multiple sclerosis is supported by …

Background Ofatumumab, a subcutaneous anti-CD20 monoclonal antibody, selectively
depletes B cells. Teriflunomide, an oral inhibitor of pyrimidine synthesis, reduces T-cell and B-…

Association between parasite infection and immune responses in multiple sclerosis - Correale
- 2007 - Annals of Neurology - Wiley Online … Jorge Correale MD … Jorge Correale MD …

Changes in gut microbiota have been associated with several diseases. Here, the International
Multiple Sclerosis Microbiome Study (iMSMS) studied the gut microbiome of 576 MS …

Neuromyelitis optica (NMO) is a chronic inflammatory autoimmune disease of the central
nervous system (CNS) characterized by acute optic neuritis (ON) and transverse myelitis (TM). …