CT angiography clot burden score and collateral score: correlation with clinical and radiologic outcomes in acute middle cerebral artery infarct

IYL Tan, AM Demchuk, J Hopyan… - American Journal …, 2009 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Clot extent, location, and collateral integrity are important
determinants of outcome in acute stroke. We hypothesized that a novel clot burden score (…

Intravenous tenecteplase compared with alteplase for acute ischaemic stroke in Canada (AcT): a pragmatic, multicentre, open-label, registry-linked, randomised …

…, J Dawe, J Stang, J Day, J Miller, J Gorman, JJ Hopyan… - The Lancet, 2022 - thelancet.com
Background Intravenous thrombolysis with alteplase bolus followed by infusion is a global
standard of care for patients with acute ischaemic stroke. We aimed to determine whether …

Benefits of GLP-1 (glucagon-like peptide 1) receptor agonists for stroke reduction in type 2 diabetes: a call to action for neurologists

…, T Fitzpatrick, JD Gilbert, S Verma, JJ Hopyan - Stroke, 2022 - Am Heart Assoc
People living with diabetes are at higher risk for stroke and have a poorer prognosis following
a stroke event than those without diabetes. Data from cardiovascular outcome trials and …

Atrial premature beats predict atrial fibrillation in cryptogenic stroke: results from the EMBRACE trial

…, P Soros, M Wright, V Basile, K Boyle, J Hopyan… - Stroke, 2015 - Am Heart Assoc
Background and Purpose— Many ischemic strokes or transient ischemic attacks are labeled
cryptogenic but may have undetected atrial fibrillation (AF). We sought to identify those most …

Hemorrhagic Transformation of Ischemic Stroke: Prediction with CT Perfusion1

RI Aviv, CD d'Esterre, BD Murphy, JJ Hopyan, B Buck… - Radiology, 2009 - pubs.rsna.org
Purpose: To determine whether admission computed tomography (CT) perfusion–derived
permeability–surface area product (PS) maps differ between patients with hemorrhagic acute …

Certainty of stroke diagnosis: incremental benefit with CT perfusion over noncontrast CT and CT angiography

J Hopyan, A Ciarallo, D Dowlatshahi, P Howard… - Radiology, 2010 - pubs.rsna.org
Purpose To systematically evaluate the diagnostic benefits and inter- and intraobserver
reliability of an incremental computed tomographic (CT) protocol in the confirmation of clinically …

Renal safety of CT angiography and perfusion imaging in the emergency evaluation of acute stroke

JJ Hopyan, DJ Gladstone, G Mallia… - American Journal …, 2008 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Multimodal CT imaging with contrast-enhanced CT
angiography (CTA) and CT perfusion (CTP) is increasingly being used to guide emergency …

Defining the CT angiography 'spot sign'in primary intracerebral hemorrhage

…, JC Kosior, DJ Gladstone, JJ Hopyan… - Canadian journal of …, 2009 - cambridge.org
Purpose:The computed tomogram angiography (CTA) ‘spot sign’ describes foci of intralesional
enhancement associated with hematoma expansion in primary intracerebral hemorrhage …

Orthostatic hypotension, cerebral hypoperfusion, and visuospatial deficits in Lewy body disorders

…, Z Shirzadi, G Kleiner-Fisman, J Lee, J Hopyan… - Parkinsonism & Related …, 2016 - Elsevier
Background Orthostatic hypotension and cognitive impairment are two non-motor attributes
of Lewy body spectrum disorders that impact independence. This proof-of-concept study …

Crescendo transient Aura attacks: a transient ischemic attack mimic caused by focal subarachnoid hemorrhage

…, RI Aviv, BM Demaerschalk, DW Dodick, J Hopyan… - Stroke, 2009 - Am Heart Assoc
Background and Purpose— Diagnosis of transient ischemic attack can be difficult because
many mimics exist. We report the clinical and neuroimaging features of a distinct hemorrhagic …