Carotid-artery imaging in the diagnosis and management of patients at risk of stroke

JM U-King-Im, V Young, JH Gillard - The Lancet Neurology, 2009 - thelancet.com
Carotid atherosclerotic disease is one of the major preventable causes of ischaemic strokes.
In clinical practice, decision making with regard to carotid endarterectomy or stenting is still …

The ATHEROMA (Atorvastatin Therapy: Effects on Reduction of Macrophage Activity) Study: evaluation using ultrasmall superparamagnetic iron oxide-enhanced …

…, MJ Graves, AJ Patterson, JM U-King-Im… - Journal of the American …, 2009 - jacc.org
Objectives : The aim of this study was to evaluate the effects of low-dose (10 mg) and high-dose
(80 mg) atorvastatin on carotid plaque inflammation as determined by ultrasmall …

Identifying inflamed carotid plaques using in vivo USPIO-enhanced MR imaging to label plaque macrophages

RA Trivedi, C Mallawarachi, JM U-King-Im… - … , and vascular biology, 2006 - Am Heart Assoc
Background— Inflammation within atherosclerotic lesions contributes to plaque instability
and vulnerability to rupture. We set out to evaluate the use of a macrophage labeling agent to …

In vivo detection of macrophages in human carotid atheroma: temporal dependence of ultrasmall superparamagnetic particles of iron oxide-enhanced MRI

RA Trivedi, JM U-King-Im, MJ Graves, JJ Cross… - Stroke, 2004 - Am Heart Assoc
Background— It has been suggested that inflammatory cells within vulnerable plaques may
be visualized by superparamagnetic iron oxide particle-enhanced MRI. The purpose of this …

Stress analysis of carotid plaque rupture based on in vivo high resolution MRI

ZY Li, S Howarth, RA Trivedi, JM U-King-Im… - Journal of …, 2006 - Elsevier
Atheromatous carotid plaque rupture is responsible for the majority of ischaemic strokes in
the developed world. Plaque rupture has been associated with plaque morphology, plaque …

Detection and evaluation of intracranial aneurysms with 16-row multislice CT angiography

G Tipper, JM U-King-Im, SJ Price, RA Trivedi, JJ Cross… - Clinical radiology, 2005 - Elsevier
AIM: The aim of this study was to assess the usefulness of 16-row multislice CT angiography
(CTA) in evaluating intracranial aneurysms, by comparison with conventional digital …

EPG5-related Vici syndrome: a paradigm of neurodevelopmental disorders with defective autophagy

S Byrne, L Jansen, JM U-King-Im, A Siddiqui… - Brain, 2016 - academic.oup.com
Vici syndrome is a progressive neurodevelopmental multisystem disorder due to recessive
mutations in the key autophagy gene EPG5. We report genetic, clinical, neuroradiological, …

MRI-derived measurements of fibrous-cap and lipid-core thickness: the potential for identifying vulnerable carotid plaques in vivo

RA Trivedi, JM U-King-Im, MJ Graves, J Horsley… - Neuroradiology, 2004 - Springer
Vulnerable plaques have thin fibrous caps overlying large necrotic lipid cores. Recent studies
have shown that high-resolution MR imaging can identify these components. We set out to …

Acute hyperammonemic encephalopathy in adults: imaging findings

JM U-King-Im, E Yu, E Bartlett… - American Journal …, 2011 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Acute hyperammonemic encephalopathy has significant
morbidity and mortality unless promptly treated. We describe the MR imaging findings of …

Imaging the vertebral artery

KY Tay, JM U-King-Im, RA Trivedi, NJ Higgins… - European …, 2005 - Springer
Although conventional intraarterial digital subtraction angiography remains the gold
standard method for imaging the vertebral artery, noninvasive modalities such as ultrasound, …