Due to lack of effective therapy, primary brain tumors are the focus of intense investigation
of novel experimental approaches that use vectors and recombinant viruses. Therapeutic …

Malignant glioma is the most common primary brain tumor and carries a grim prognosis,
with a median survival of just over 14 months. Given the poor outcomes with standard-of-care …

Brain metastases are a challenging manifestation of renal cell carcinoma. We have a limited
understanding of brain metastasis tumor and immune biology, drivers of resistance to …

G207 is a conditionally replicating derivative of herpes simplex virus (HSV) type-1 strain F
engineered with deletions of both γ 1 34.5 loci and a lacZ insertion disabling the UL 39 gene. …

Malignant gliomas are the most common malignant brain tumors and are almost always fatal.
A thymidine kinase-negative mutant of herpes simplex virus-1 (dlsptk) that is attenuated for …

The NMR pulsed magnetic field gradient stimulated echo technique of Tanner is especially
useful for measuring the translational diffusion coefficient, D, of the resonant nucleus in …

HADES is a versatile magnetic spectrometer aimed at studying dielectron production in pion,
proton and heavy-ion-induced collisions. Its main features include a ring imaging gas …

THE known copper oxide superconductors all have intergrowth structures consisting of
superconducting layers of fixed oxygen content alternating with non-superconducting oxide layers…

ONYX-015 is an oncolytic virus untested as a treatment for malignant glioma. The NABTT
CNS Consortium conducted a dose-escalation trial of intracerebral injections of ONYX-015. …

We have previously demonstrated safety of G207, a doubly mutated (deletion of both γ 1
34.5 loci, insertional inactivation of U L 39) herpes simplex virus (HSV) for patients …