BACKGROUND AND PURPOSE: Cognitive impairment is a common, disabling symptom of
MS. We investigated the impact of cerebral perfusion and brain and lesion volumetry on …

BACKGROUND AND PURPOSE: There is increasing evidence implicating microvascular
impairment in MS pathogenesis. Perfusion imaging offers a unique opportunity to investigate …

The singular value decomposition deconvolution of cerebral tissue concentration–time
curves with the arterial input function is commonly used in dynamic susceptibility contrast …

Purpose To compare quantitative values of cerebral blood flow (CBF) derived from dynamic
susceptibility contrast (DSC) magnetic resonance (MR) imaging with reference standard …

The Bookend technique is a magnetic resonance imaging (MRI) dynamic susceptibility
contrast method that provides reliable quantitative measurement of cerebral blood flow (CBF) …

DSC-PWI suffers from blooming, clipping, and saturation effects in large vessels, which
make arterial input function (AIF) determination unreliable. To combat this, we used a dual-…

Quantitative cerebral perfusion is a fundamental physiologic parameter that reflects the
severity and progression of a broad range of pathologies. Quantitative cerebral blood flow (qCBF…

Cerebrovascular reserve (CVR) measures the autoregulatory dilatation of intracranial vessels
in the setting of ischemic pathologies. Quantitative cerebral blood flow scans prior to and …

A new correction model for arterial-tissue delay and dispersion in dynamic susceptibility
contrast MR imaging has been developed. It is shown to provide more accurate cerebral blood …

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