Sympathetic nervous system behavior in human obesity
KP Davy, JS Orr - Neuroscience & biobehavioral reviews, 2009 - Elsevier
… Jeb Orr was supported by an American Heart Association predoctoral fellowship. … RS
Ahima, JS Flier … CL Gentile, JS Orr, BM Davy, KP Davy …
Ahima, JS Flier … CL Gentile, JS Orr, BM Davy, KP Davy …
Optimized dietary strategies to protect skeletal muscle mass during periods of unavoidable energy deficit
SM Pasiakos, LM Margolis, JS Orr - The FASEB Journal, 2015 - Wiley Online Library
… Pasiakos, SM, Margolis, LM, and Orr, JS Optimized dietary strategies to protect skeletal
muscle mass during periods of unavoidable energy deficit. FASEB J. 29, 1136–1142 (2015). …
muscle mass during periods of unavoidable energy deficit. FASEB J. 29, 1136–1142 (2015). …
Arterial destiffening with weight loss in overweight and obese middle-aged and older adults
AL Dengo, EA Dennis, JS Orr, EL Marinik, E Ehrlich… - …, 2010 - Am Heart Assoc
We tested the hypothesis that weight loss via a hypocaloric diet would reduce arterial
stiffness in overweight and obese middle-aged and older adults. Thirty-six individuals were …
stiffness in overweight and obese middle-aged and older adults. Thirty-six individuals were …
Toll-like receptor 4 deficiency promotes the alternative activation of adipose tissue macrophages
JS Orr, MJ Puglisi, KLJ Ellacott, CN Lumeng… - Diabetes, 2012 - Am Diabetes Assoc
Obesity is characterized by adipose tissue (AT) macrophage (ATM) accumulation, which
promotes AT inflammation and dysfunction. Toll-like receptor 4 (TLR4) deficiency attenuates AT …
promotes AT inflammation and dysfunction. Toll-like receptor 4 (TLR4) deficiency attenuates AT …
Obesity alters adipose tissue macrophage iron content and tissue iron distribution
JS Orr, A Kennedy, EK Anderson-Baucum… - Diabetes, 2014 - Am Diabetes Assoc
Adipose tissue (AT) expansion is accompanied by the infiltration and accumulation of AT
macrophages (ATMs), as well as a shift in ATM polarization. Several studies have implicated …
macrophages (ATMs), as well as a shift in ATM polarization. Several studies have implicated …
Large artery stiffening with weight gain in humans: role of visceral fat accumulation
We tested the hypothesis that weight gain would increase arterial stiffness in healthy nonobese
adults. To address this, we overfed 14 nonobese men (age: 23±1 years) ≈1000 kcal/d …
adults. To address this, we overfed 14 nonobese men (age: 23±1 years) ≈1000 kcal/d …
Pre‐meal water consumption reduces meal energy intake in older but not younger subjects
EL Van Walleghen, JS Orr, CL Gentile, BM Davy - Obesity, 2007 - Wiley Online Library
Objective: To determine whether the consumption of water 30 minutes before an ad libitum
meal reduces meal energy intake in young and older adults. Research Methods and …
meal reduces meal energy intake in young and older adults. Research Methods and …
Imaging of the brain by nuclear magnetic resonance
A nuclear magnetic resonance (NMR) machine constructed by Thorn-EMI Ltd was used to
produce tomographic images of the brain in eight volunteers and fourteen patients. The use of …
produce tomographic images of the brain in eight volunteers and fourteen patients. The use of …
Arterial destiffening with atorvastatin in overweight and obese middle-aged and older adults
JS Orr, AL Dengo, JM Rivero, KP Davy - Hypertension, 2009 - Am Heart Assoc
We hypothesized that atorvastatin (ATOR) treatment would reduce arterial stiffness in
overweight and obese middle-aged and older adults. Twenty-six (11 men and 15 women) …
overweight and obese middle-aged and older adults. Twenty-six (11 men and 15 women) …
Isolation of adipose tissue immune cells
JS Orr, AJ Kennedy, AH Hasty - JoVE (Journal of Visualized Experiments), 2013 - jove.com
The discovery of increased macrophage infiltration in the adipose tissue (AT) of obese rodents
and humans has led to an intensification of interest in immune cell contribution to local …
and humans has led to an intensification of interest in immune cell contribution to local …