User profiles for J.-B. Hövener

Jan-Bernd Hövener

Professor and Emmy Noether Fellow, Translational MRI, Univ. Kiel
Verified email at rad.uni-kiel.de
Cited by 3205

Parahydrogen‐based hyperpolarization for biomedicine

JB Hövener, AN Pravdivtsev, B Kidd… - Angewandte Chemie …, 2018 - Wiley Online Library
Magnetic resonance (MR) is one of the most versatile and useful physical effects used for
human imaging, chemical analysis, and the elucidation of molecular structures. However, its …

Parahydrogen‐Induced Polarization of Amino Acids

…, SB Duckett, IV Koptyug, JB Hövener - Angewandte Chemie …, 2021 - Wiley Online Library
Nuclear magnetic resonance (NMR) has become a universal method for biochemical and
biomedical studies, including metabolomics, proteomics, and magnetic resonance imaging (…

In Vivo Metabolic Imaging of [1‐13C]Pyruvate‐d3 Hyperpolarized By Reversible Exchange With Parahydrogen**

…, S Korchak, S Glöggler, JB Hövener… - Angewandte Chemie …, 2023 - Wiley Online Library
Metabolic magnetic resonance imaging (MRI) using hyperpolarized (HP) pyruvate is becoming
a non‐invasive technique for diagnosing, staging, and monitoring response to treatment …

A hyperpolarized equilibrium for magnetic resonance

JB Hövener, N Schwaderlapp, T Lickert… - Nature …, 2013 - nature.com
Nuclear magnetic resonance spectroscopy and imaging (MRI) play an indispensable role in
science and healthcare but use only a tiny fraction of their potential. No more than ≈10 ppm …

Toward Biocompatible Nuclear Hyperpolarization Using Signal Amplification by Reversible Exchange: Quantitative in Situ Spectroscopy and High-Field Imaging

JB Hövener, N Schwaderlapp, R Borowiak… - Analytical …, 2014 - ACS Publications
Signal amplification by reversible exchange (SABRE) of a substrate and parahydrogen at a
catalytic center promises to overcome the inherent insensitivity of magnetic resonance. In …

PASADENA hyperpolarization of 13C biomolecules: equipment design and installation

JB Hövener, EY Chekmenev, KC Harris… - … Resonance Materials in …, 2009 - Springer
Object The PASADENA method has achieved hyperpolarization of 16–20% (exceeding
40,000-fold signal enhancement at 4.7 T), in liquid samples of biological molecules relevant to in …

Instrumentation for hydrogenative parahydrogen-based hyperpolarization techniques

AB Schmidt, CR Bowers, K Buckenmaier… - Analytical …, 2022 - ACS Publications
The unique properties of the entangled, antisymmetric nuclear spin state of dihydrogen,
parahydrogen (pH2), has intrigued physicists, chemists, and other scientists for almost a century. …

Dental MRI using wireless intraoral coils

…, D Von Elverfeldt, O Herdt, T Flügge, JB Hövener - Scientific reports, 2016 - nature.com
Currently, the gold standard for dental imaging is projection radiography or cone-beam
computed tomography (CBCT). These methods are fast and cost-efficient, but exhibit poor soft …

A continuous‐flow, high‐throughput, high‐pressure parahydrogen converter for hyperpolarization in a clinical setting

JB Hövener, S Bär, J Leupold, K Jenne… - NMR in …, 2013 - Wiley Online Library
Pure parahydrogen (pH 2 ) is the prerequisite for optimal pH 2 ‐based hyperpolarization
experiments, promising approaches to access the hidden orders of magnitude of MR signals. …

Dental MRI: imaging of soft and solid components without ionizing radiation

JB Hövener, S Zwick, J Leupold… - Journal of Magnetic …, 2012 - Wiley Online Library
Dental MRI: Imaging of soft and solid components without ionizing radiation - Hövener - 2012
- Journal of Magnetic Resonance Imaging - Wiley Online Library … Jan-Bernd Hövener PhD …