[HTML][HTML] Aberrant signaling pathways in glioma

…, T Watanabe, Y Hayashi, L Teng, IV Pyko, JI Hamada - Cancers, 2011 - mdpi.com
Glioblastoma multiforme (GBM), a WHO grade IV malignant glioma, is the most common
and lethal primary brain tumor in adults; few treatments are available. Median survival rates …

The influence of sex and the presence of giant cells on postoperative long-term survival in adult patients with supratentorial glioblastoma multiforme

N Shinojima, M Kochi, JI Hamada, H Nakamura… - Journal of …, 2004 - thejns.org
Object. Glioblastoma multiforme (GBM) remains incurable by conventional treatments,
although some patients experience long-term survival. A younger age, a higher Karnofsky …

[HTML][HTML] Ischemia-induced neuronal cell death is mediated by the endoplasmic reticulum stress pathway involving CHOP

…, S Yano, M Morioka, T Gotoh, JI Hamada… - Cell Death & …, 2004 - nature.com
Brain ischemia induces apoptosis in neuronal cells, but the mechanism is not well understood.
When wild-type mice were subjected to bilateral common carotid arteries occlusion (…

Potential role of calcineurin for brain ischemia and traumatic injury

M Morioka, JI Hamada, Y Ushio, E Miyamoto - Progress in neurobiology, 1999 - Elsevier
Calcineurin belongs to the family of Ca 2+ /calmodulin-dependent protein phosphatase,
protein phosphatase 2B. Calcineurin is the only protein phosphatase which is regulated by a …

Spatial and temporal variations of the rainy season over Indonesia and their link to ENSO

JI Hamada, MD YAMANAKA, J Matsumoto… - Journal of the …, 2002 - jstage.jst.go.jp
… The first author (Hamada) started this work at RASC (as of April 1,2000, Radio Atmospheric
… (1961– 90) which have been listed in Hamada and Sribimawati (1998). We have selected …

[HTML][HTML] Silencing of ferrochelatase enhances 5-aminolevulinic acid-based fluorescence and photodynamic therapy efficacy

…, E Nambu, IV Pyko, Y Hayashi, JI Hamada - British journal of …, 2011 - nature.com
Background: Recurrence of glioma frequently occurs within the marginal area of the
surgical cavity due to invading residual cells. 5-Aminolevulinic acid (5-ALA) fluorescence-guided …

Angiographic dilatation and branch extension of the anterior choroidal and posterior communicating arteries are predictors of hemorrhage in adult moyamoya patients

M Morioka, JI Hamada, T Kawano, T Todaka, S Yano… - Stroke, 2003 - Am Heart Assoc
Background and Purpose— The cause of intracranial bleeding in moyamoya disease
patients is still unknown. To identify factors that contribute to bleeding, we assessed the …

Suramin. A potent inhibitor of melanoma heparanase and invasion

…, A DeChavigny, CE Johnson, JI Hamada… - Journal of Biological …, 1991 - Elsevier
Suramin, a polysulfonated naphthylurea, has anti-reverse transcriptase and anti-proliferative
activities and inhibits the binding of various growth factors to their cell surface receptors. …

[HTML][HTML] Integrin α3 is overexpressed in glioma stem-like cells and promotes invasion

…, Y Sai, T Tsuji, KI Miyamoto, A Hirao, JI Hamada - British journal of …, 2013 - nature.com
Background: Glioma stem-like cell (GSC) properties are responsible for gliomagenesis and
recurrence. GSCs are invasive but its mechanism remains to be elucidated. Here, we …

Diurnal variation of precipitable water over a mountainous area of Sumatra Island

P Wu, JI Hamada, S Mori, YI Tauhid… - Journal of Applied …, 2003 - journals.ametsoc.org
Diurnal variations in atmospheric water vapor at Koto Tabang, a mountainous area of
Sumatra Island, Indonesia, are studied by analyzing the GPS-derived precipitable water, …