[HTML][HTML] A highly annotated whole-genome sequence of a Korean individual
Recent advances in sequencing technologies have initiated an era of personal genome
sequences. To date, human genome sequences have been reported for individuals with …
sequences. To date, human genome sequences have been reported for individuals with …
Abnormal splicing of the leptin receptor in diabetic mice
…, JM Montez, KM Carroll, JG Darvishzadeh, JI Lee… - Nature, 1996 - nature.com
MUTATIONS in the mouse diabetes(db) gene result in obesity and diabetes in a syndrome
resembling morbid human obesity 1 . Previous data suggest that the db gene encodes the …
resembling morbid human obesity 1 . Previous data suggest that the db gene encodes the …
ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex
The ataxia-telangiectasia mutated (ATM) kinase signals the presence of DNA double-strand
breaks in mammalian cells by phosphorylating proteins that initiate cell-cycle arrest, …
breaks in mammalian cells by phosphorylating proteins that initiate cell-cycle arrest, …
The trajectory of loneliness in response to COVID-19.
Social distancing and “stay-at-home” orders are essential to contain the coronavirus outbreak
(COVID-19), but there is concern that these measures will increase feelings of loneliness, …
(COVID-19), but there is concern that these measures will increase feelings of loneliness, …
Large-scale association analysis identifies new risk loci for coronary artery disease
Coronary artery disease (CAD) is the commonest cause of death. Here, we report an
association analysis in 63,746 CAD cases and 130,681 controls identifying 15 loci reaching …
association analysis in 63,746 CAD cases and 130,681 controls identifying 15 loci reaching …
Multifunctional wearable devices for diagnosis and therapy of movement disorders
Wearable systems that monitor muscle activity, store data and deliver feedback therapy are
the next frontier in personalized medicine and healthcare. However, technical challenges, …
the next frontier in personalized medicine and healthcare. However, technical challenges, …
[HTML][HTML] Single-cell RNA sequencing technologies and bioinformatics pipelines
Rapid progress in the development of next-generation sequencing (NGS) technologies in
recent years has provided many valuable insights into complex biological systems, ranging …
recent years has provided many valuable insights into complex biological systems, ranging …
Hypoxia-inducible factor (HIF-1) α: its protein stability and biological functions
JW Lee, SH Bae, JW Jeong, SH Kim… - Experimental & molecular …, 2004 - nature.com
Hypoxia-inducible factor (HIF-1) is an oxygen-dependent transcriptional activator, which plays
crucial roles in the angiogenesis of tumors and mammalian development. HIF-1 consists …
crucial roles in the angiogenesis of tumors and mammalian development. HIF-1 consists …
Flipping bits in memory without accessing them: An experimental study of DRAM disturbance errors
Memory isolation is a key property of a reliable and secure computing system--an access to
one memory address should not have unintended side effects on data stored in other …
one memory address should not have unintended side effects on data stored in other …
Cohort profile: the national health insurance service–national sample cohort (NHIS-NSC), South Korea
J Lee, JS Lee, SH Park, SA Shin… - International journal of …, 2017 - academic.oup.com
The National Health Insurance Service–National Sample Cohort (NHIS-NSC) is a population-based
cohort established by the National Health Insurance Service (NHIS) in South Korea. …
cohort established by the National Health Insurance Service (NHIS) in South Korea. …