User profiles for J.J. Corrigan

Joshua J. Corrigan

Department of Biological Engineering, Massachusetts Institute of Technology
Verified email at mit.edu
Cited by 417

D-Amino Acids in Animals: Novel reactions and compounds unique to specific stages of development characterize this subject.

JJ Corrigan - Science, 1969 - science.org
Molecular asymmetry is' fundamental to all known living systems. It plays a major role in
enzymatic specificityand dictates the spatial architecture ofmany biological polymers. The …

Autoimmune encephalitis: pathophysiology and imaging review of an overlooked diagnosis

…, SC Patel, HL Marin, JJ Corrigan… - American Journal …, 2017 - Am Soc Neuroradiology
Autoimmune encephalitis is a relatively new category of immune-mediated disease
involving the central nervous system that demonstrates a widely variable spectrum of clinical …

Hemolytic-uremic syndrome

JJ Corrigan Jr, FG Boineau - Pediatrics in Review, 2001 - publications.aap.org
The hemolytic-uremic syndrome (HUS) has been recognized for more than 45 years and
consists of the combination of hemolytic anemia, thrombocytopenia, and acute renal failure. …

Changes in the blood coagulation system associated with septicemia

JJ Corrigan Jr, WL Ray, N May - New England Journal of …, 1968 - Mass Medical Soc
Detailed coagulation analyses in 36 pediatric cases of septicemia revealed 22 gram-negative
and eight gram-positive infections, two Rocky Mountain spotted fevers, and four with no …

Guidelines for pediatric cancer centers.

JJ Corrigan, SA Feig - Pediatrics, 2004 - europepmc.org
Since the American Academy of Pediatrics published guidelines for pediatric cancer centers
in 1986 and 1997, significant changes in the delivery of health care have prompted a review …

Coagulopathy associated with vitamin E ingestion

JJ Corrigan, FI Marcus - Jama, 1974 - jamanetwork.com
Although hypervitaminosis E causes a prolonged prothrombin time and a hemorrhagic state
in animals, excessive vitamin E has not previously been found to cause bleeding in normal …

Naturally occurring hypothermia is more advantageous than fever in severe forms of lipopolysaccharide-and Escherichia coli-induced systemic inflammation

…, A Singh, VA Kulchitsky, JJ Corrigan… - American Journal …, 2012 - journals.physiology.org
The natural switch from fever to hypothermia observed in the most severe cases of systemic
inflammation is a phenomenon that continues to puzzle clinicians and scientists. The …

TRPV 1 antagonists that cause hypothermia, instead of hyperthermia, in rodents: compounds' pharmacological profiles, in vivo targets, thermoeffectors recruited and …

…, RM Reilly, A Gomtsyan, JJ Corrigan… - Acta …, 2018 - Wiley Online Library
Aim Thermoregulatory side effects hinder the development of transient receptor potential
vanilloid‐1 ( TRPV 1) antagonists as new painkillers. While many antagonists cause …

Hemostatic markers in acute stroke.

WM Feinberg, DC Bruck, ME Ring, JJ Corrigan Jr - Stroke, 1989 - Am Heart Assoc
To assess the time course of thrombosis and fibrinolysis after acute stroke, we measured
concentrations of fibrinopeptide A (FpA), B-beta 1-42 peptide (B-beta 1-42), B-beta 15-42 …

Heparin therapy in septicemia with disseminated intravascular coagulation: effect on mortality and on correction of hemostatic defects

JJ Corrigan Jr, CM Jordan - New England Journal of Medicine, 1970 - Mass Medical Soc
Of 26 children with septic shock studied for coagulation defects, 24 received heparin in
addition to standard therapy. Disseminated intravascular coagulation was diagnosed in 96 per …