Diagnostic accuracy of CT perfusion imaging for detecting acute ischemic stroke: a systematic review and meta-analysis

JM Biesbroek, JM Niesten, JW Dankbaar… - Cerebrovascular …, 2013 - karger.com
Background: The aim of the current study was to determine the sensitivity and specificity of CT
perfusion (CTP) for the detection of ischemic stroke by performing a systematic review and …

[HTML][HTML] Histopathologic composition of cerebral thrombi of acute stroke patients is correlated with stroke subtype and thrombus attenuation

JM Niesten, IC van der Schaaf, L van Dam, A Vink… - PLoS …, 2014 - journals.plos.org
Introduction We related composition of cerebral thrombi to stroke subtype and attenuation on
non-contrast CT (NCCT) to gain more insight in etiopathogenesis and to validate thrombus …

The prognostic value of CT angiography and CT perfusion in acute ischemic stroke

…, JW Dankbaar, AD Horsch, JM Niesten… - Cerebrovascular …, 2015 - karger.com
Background: CT angiography (CTA) and CT perfusion (CTP) are important diagnostic tools
in acute ischemic stroke. We investigated the prognostic value of CTA and CTP for clinical …

Permeable thrombi are associated with higher intravenous recombinant tissue-type plasminogen activator treatment success in patients with acute ischemic stroke

…, WP Mali, T van Seeters, JM Niesten… - Stroke, 2016 - Am Heart Assoc
Background and Purpose— Preclinical studies showed that thrombus permeability improves
recombinant tissue-type plasminogen activator (r-tPA) efficacy. We hypothesize that …

Additional diagnostic value of computed tomography perfusion for detection of acute ischemic stroke in the posterior circulation

…, JW Dankbaar, A Algra, JA Vos, JM Niesten… - Stroke, 2015 - Am Heart Assoc
Background and Purpose— Detection of acute infarction in the posterior circulation is
challenging. We aimed to determine the additional value of tomograpy (CT) perfusion to …

[HTML][HTML] Prediction of outcome in patients with suspected acute ischaemic stroke with CT perfusion and CT angiography: the Dutch acute stroke trial (DUST) study …

…, JW Dankbaar, AD Horsch, MJA Luitse, JM Niesten… - BMC neurology, 2014 - Springer
Background Prediction of clinical outcome in the acute stage of ischaemic stroke can be
difficult when based on patient characteristics, clinical findings and on non-contrast CT. CT …

[HTML][HTML] Risk factors for atherosclerotic and medial arterial calcification of the intracranial internal carotid artery

…, WP Mali, T van Seeters, AD Horsch, JM Niesten… - Atherosclerosis, 2018 - Elsevier
Background and aims Calcifications of the intracranial internal carotid artery (iICA) are an
important risk factor for stroke. The calcifications can occur both in the intimal and medial layer …

Predictive value of thrombus attenuation on thin-slice non-contrast CT for persistent occlusion after intravenous thrombolysis

JM Niesten, IC Van Der Schaaf… - Cerebrovascular …, 2014 - karger.com
Background: In stroke erythrocyte-rich thrombi are more sensitive to intravenous thrombolysis
with recombinant tissue plasminogen activator (IV-rtPA) and have higher density on non-…

[HTML][HTML] Reliability of visual assessment of non-contrast CT, CT angiography source images and CT perfusion in patients with suspected ischemic stroke

T Van Seeters, GJ Biessels, JM Niesten… - PloS one, 2013 - journals.plos.org
Background and Purpose Good reliability of methods to assess the extent of ischemia in
acute stroke is important for implementation in clinical practice, especially between observers …

Radiation dose reduction in cerebral CT perfusion imaging using iterative reconstruction

JM Niesten, IC van der Schaaf, AJ Riordan… - European …, 2014 - Springer
Objectives To investigate whether iterative reconstruction (IR) in cerebral CT perfusion (CTP)
allows for 50 % dose reduction while maintaining image quality (IQ). Methods A total of 48 …