T 1 black holes (BHs) on MRIs may represent either areas of oedema or axonal loss in
patients with multiple sclerosis. BHs begin as contrast enhancing lesions (CELs) and evolve …

Background Fatigue is a common and disabling symptom of multiple sclerosis (MS). Previous
studies reported that damage of the corticostriatothalamocortical circuit is critical in its …

BACKGROUND AND PURPOSE: Several studies suggest that grey matter involvement may
play a role in multiple sclerosis (MS) pathology. Diffusion tensor imaging (DTI) at 3T was …

In recent years, human herpesvirus 6 (HHV-6) has been investigated as a possible causative
agent for MS. To determine if the detection of HHV-6 DNA in the serum of MS patients …

The HLA region, and particularly the DR15 haplotype (containing the two DRB* genes
DRB1*1501 and DRB5*0101 and the tightly linked DQ alleles DQA*0102 and DQB1*0602, which …

BACKGROUND AND PURPOSE We investigated the impact of focal and diffuse corticospinal
tracts damage on sensory‐motor disability in multiple sclerosis (MS) patients. METHODS …

BACKGROUND AND PURPOSE:In vivo detection of cortical lesions in patients with multiple
sclerosis (MS) by MR imaging is hampered by several factors. Among them is the low …

BACKGROUND AND PURPOSE Postmortem studies in multiple sclerosis (MS) indicate that
in some white matter lesions (WM‐Ls), iron is detectable with T 2 *‐weighted (T 2 *‐w), and …

BACKGROUND AND PURPOSE: Brains of patients with multiple sclerosis (MS) characteristically
have “black holes” (BHs), hypointense lesions on T1-weighted (T1W) spin-echo (SE) …

BACKGROUND AND PURPOSE Using high‐field magnetic resonance imaging (MRI), we
investigated the relationships between white matter (WM) lesion volume (LV), normal‐…