The diagnosis of bone metastases is an event with certain consequences for the patient.
They often mean pain and can also mean pathological fractures, hypercalcemia, and spinal …

Background Isocitrate dehydrogenase (IDH)–mutant grade 2 gliomas are malignant brain
tumors that cause considerable disability and premature death. Vorasidenib, an oral brain-…

Importance Clinical outcomes for glioblastoma remain poor. Treatment with immune
checkpoint blockade has shown benefits in many cancer types. To our knowledge, data from a …

Background Addition of temozolomide (TMZ) to radiotherapy (RT) improves overall survival (OS)
in patients with glioblastoma (GBM), but previous studies suggest that patients with …

Urothelial bladder cancer (UC) is the most common malignancy involving the urinary system
and represents a significant health problem. Immunotherapy has been used for decades for …

BACKGROUND AND PURPOSE: In cerebral gliomas, rCBV correlates with tumor grade and
histologic findings of vascular proliferation. Moreover, ADC assesses water diffusivity and is …

… Dr Sepúlveda reports personal fees and non-financial support from AbbVie, during the
conduct of the study; grants from Pfizer, personal fees and non-financial support from Celgene, …

Glioblastoma multiforme (GBM) is the most frequent and aggressive type of brain tumor due,
at least in part, to its poor response to current anticancer treatments. These features could …

A high percentage of patients with brain metastases frequently develop neurocognitive
symptoms; however, understanding how brain metastasis co-opts the function of neuronal circuits …

Glioblastomas (GBM) are devastating tumors in which there has been little clinical improvement
in the last decades. New molecularly directed therapies are under development. EGFR …