PURPOSE: Lennox–Gastaut syndrome (LGS) is an epileptogenic disorder that arises in
childhood and is typically characterized by multiple seizure types, slow spike-and-wave …

Alzheimer's disease (AD) is characterized by the deposition of senile plaques (SPs) and
neurofibrillary tangles (NFTs) in vulnerable brain regions. SPs are composed of aggregated β-…

… JP-MS analysis confirmed that levels of both A131-•0 and Al311-•0 were reduced by 1713-E…
Vincent, B., Beaudet, A., Oauch, P., Vincent, JP, & Checler, F. Distinct properties of neuronal …

The excessive generation and accumulation of 40- and 42-aa β-amyloid peptides (Aβ 40 /Aβ
42 ) in selectively vulnerable brain regions is a major neuropathological feature of …

Alzheimer's disease (AD) is characterized by the age-related deposition of β-amyloid (Aβ)
40/42 peptide aggregates in vulnerable brain regions. Multiple levels of evidence implicate a …

We report a comprehensive proteogenomics analysis, including whole-genome sequencing,
RNA sequencing, and proteomics and phosphoproteomics profiling, of 218 tumors across 7 …

Studies of inflammatory mediators have established the tumor micro-environment as a driver
of oncogenesis. This inflammatory milieu often precedes cancer, however recent data also …

BACKGROUND: The endoscopic, endonasal, extended transsphenoidal approach is a
minimal-access technique for managing craniopharyngiomas. Outcome measures such as return …

Background The coronavirus disease 2019 (COVID-19) pandemic has created significant
obstacles within medical education. For medical students interested in pursuing neurosurgery …

… There is however significant variation in the incidence by geographic region with a much
higher incidence in Japan (4.8-15%) than Western countries (.3-3.4%). The suprasellar region …