User profiles for J.P. Leite

Joao Pereira Leite

Universidade de Sao Paulo
Verified email at fmrp.usp.br
Cited by 10995

Review of G and P typing results from a global collection of rotavirus strains: implications for vaccine development

…, M Ramachandran, BK Das, JP Leite… - Journal of Infectious …, 1996 - academic.oup.com
Candidate rotavirus vaccines have been prepared with reassortant strains specifically to protect
against the 4 major rotavirus G serotypes (Gl-4). Many studies using P (VP4) genotyping …

Animal models of epilepsy: use and limitations

…, LS Bueno-Junior, JP Leite - Neuropsychiatric …, 2014 - Taylor & Francis
Epilepsy is a chronic neurological condition characterized by recurrent seizures that affects
millions of people worldwide. Comprehension of the complex mechanisms underlying …

Spontaneous recurrent seizures in rats: an experimental model of partial epilepsy

JP Leite, ZA Bortolotto, EA Cavalheiro - Neuroscience & Biobehavioral …, 1990 - Elsevier
Seizures induced by pilocarpine (PILO) have proven to be a useful procedure for investigating
the basic mechanisms essential for generation, spread and motor expression of seizures …

Long‐term effects of pilocarpine in rats: structural damage of the brain triggers kindling and spontaneous I recurrent seizures

EA Cavalheiro, JP Leite, ZA Bortolotto, WA Turski… - …, 1991 - Wiley Online Library
Structural damage of the human brain (perinatal damage, cerebral trauma, head injury,
cerebrovascular and degenerative diseases, intracranial tumor, metabolic diseases, toxins, drug‐…

Validation of the National Institutes of Health Stroke Scale, modified Rankin Scale and Barthel Index in Brazil: the role of cultural adaptation and structured …

…, DF Pereira, E Pinto, JP Leite… - Cerebrovascular …, 2009 - karger.com
Background: We aimed to validate three widely used scales in stroke research in a
multiethnic Brazilian population. Methods: The National Institutes of Health Stroke Scale (NIHSS), …

Hippocampal GABA and glutamate transporter immunoreactivity in patients with temporal lobe epilepsy

…, Y Dehnes, NC Danbolt, N Nelson, JP Leite… - Neurology, 1999 - AAN Enterprises
Objective: Sodium-coupled transporters remove extracellular neurotransmitters and alterations
in their function could enhance or suppress synaptic transmission and seizures. This …

Hippocampal neuron damage in human epilepsy: Meyer's hypothesis revisited

GW Mathern, PD Adelson, LD Cahan, JP Leite - Progress in brain research, 2002 - Elsevier
Whether hippocampal neuron loss and/or hippocampal sclerosis is the ‘cause’ or ‘consequence’
of seizures has been a fundamental question in human epilepsy studies for over a …

New insights from the use of pilocarpine and kainate models

JP Leite, N Garcia-Cairasco, EA Cavalheiro - Epilepsy research, 2002 - Elsevier
Local or systemic administration of pilocarpine and kainate in rodents leads to a pattern of
repetitive limbic seizures and status epilepticus, which can last for several hours. A latent …

[HTML][HTML] Use of quantitative molecular diagnostic methods to assess the aetiology, burden, and clinical characteristics of diarrhoea in children in low-resource settings …

…, M Gottlieb, RL Guerrant, AAM Lima, JP Leite… - The Lancet Global …, 2018 - thelancet.com
Background Optimum management of childhood diarrhoea in low-resource settings has been
hampered by insufficient data on aetiology, burden, and associated clinical characteristics. …

[HTML][HTML] Use of quantitative molecular diagnostic methods to investigate the effect of enteropathogen infections on linear growth in children in low-resource settings …

…, M Gottlieb, RL Guerrant, AAM Lima, JP Leite… - The Lancet Global …, 2018 - thelancet.com
Background Enteropathogen infections in early childhood not only cause diarrhoea but
contribute to poor growth. We used molecular diagnostics to assess whether particular …