One of the most common problems associated with radiopharmaceuticals is an unanticipated
or altered biodistribution, which can have a significant clinical impact on safety, scan …

Prostate cancer (CaP) is the most common noncutaneous malignancy affecting men in North
America. Despite significant efforts, conventional imaging of CaP does not contribute to …

Determining the genetic basis of cancer requires comprehensive analyses of large collections
of histopathologically well-classified primary tumours. Here we report the results of a …

Background The genetic alterations responsible for an adverse outcome in most patients
with acute myeloid leukemia (AML) are unknown. Methods Using massively parallel DNA …

Acute myeloid leukaemia is a highly malignant haematopoietic tumour that affects about
13,000 adults in the United States each year. The treatment of this disease has changed little in …

Somatic alterations in cellular DNA underlie almost all human cancers 1 . The prospect of
targeted therapies 2 and the development of high-resolution, genome-wide approaches 3 , 4 , …

Importance Black men are more likely to die of prostate cancer than white men. In men with
similar stages of disease, the contribution of biological vs nonbiological differences to this …

Importance Although poorly understood, there is heterogeneity in the molecular biology of
cancer across race and ethnicities. The representation of racial minorities in large genomic …

Purpose: Standard imaging for assessing osseous metastases in advanced prostate cancer
remains focused on altered bone metabolism and is inadequate for diagnostic, prognostic, …

We conducted a prospective study to evaluate bone bruises, or trabecular microfractures,
associated with isolated medial collateral ligament injuries. Magnetic resonance imaging was …