Context: Access to transportation to transverse the large distances between residences and
health services in rural settings is a necessity. However, little research has examined directly …

• Adrenoleukodystrophy was diagnosed pathologically in 17 male patients. The diagnosis
was suggested by clinical and laboratory signs of primary adrenal failure and by neurological …

X-linked adrenoleukodystrophy (X-ALD) is a peroxisomal disorder with impaired β-oxidation
of very long chain fatty acids (VLCFAs) and reduced function of peroxisomal very long chain …

Prominent inflammation in the demyelinative lesion of adreno-leukodystrophy (ALD) has
suggested an immune-mediated pathogenetic component. Commercially available antibodies …

Originally described and most frequently reported in association with the kidney, the
malignant rhabdoid tumor (MRT) is a highly aggressive neoplasm with distinctive morphologic …

Neurological dysfunction is a prominent feature of most peroxisomal disorders. Enormous
progress in defining their gene defects has been achieved. The genes and gene products, …

The neuropathologic features of adrenomyeloneuropathy (AMN) are reviewed by supplementing
those few previously published cases with 5 additional cases collected over the years. …

Vanishing white matter (VWM) is one of the most prevalent inherited childhood
leukoencephalopathies, but this may affect people ofall ages, including neonates and adults. It is a …

Mutations in the CLN3 gene are responsible for the neurodegenerative disorder Batten
disease; however, the molecular basis of this disease remains unknown. In studying a mouse …

Evidence for a candidate multiple sclerosis (MS) virus, human herpesvirus 6 (HHV-6), was
sought in biopsy specimens of acute lesions that presented clinically as cerebral tumors …