Objective Neuromyelitis optica (NMO) attacks often are severe, are difficult to treat, and leave
residual deficits. Here, we analyzed the frequency, sequence, and efficacy of therapies …

Multiple sclerosis (MS) is a devastating inflammatory disease of the brain and spinal cord
that is thought to result from an autoimmune attack directed against antigens in the central …

Objective To analyze whether 1 of the 2 apheresis techniques, therapeutic plasma exchange
(PE) or immunoadsorption (IA), is superior in treating neuromyelitis optica spectrum …

Background and Objectives To evaluate the long-term safety and efficacy of tocilizumab (TCZ),
a humanized anti–interleukin-6 receptor antibody in myelin oligodendrocyte glycoprotein–…

Objective To analyse predictors for relapses and number of attacks under different immunotherapies
in patients with neuromyelitis optica spectrum disorder (NMOSD). Design This is a …

We conducted a genome-wide association study (GWAS) on multiple sclerosis (MS)
susceptibility in German cohorts with 4888 cases and 10,395 controls. In addition to associations …

Background: Multiple sclerosis (MS) is characterised by accelerated brain atrophy, which
relates to disease progression. Previous research shows that progressive resistance training (…

The term ‘neuromyelitis optica spectrum disorders’ (NMOSD) is used as an umbrella term
that refers to aquaporin-4 immunoglobulin G (AQP4-IgG)-positive neuromyelitis optica (NMO) …

Since December 2019, a novel coronavirus, also called severe acute respiratory syndrome
CoV-2 (SARS-CoV-2), emerged in Wuhan, China, and caused a pandemic disease (COVID-…

Objectives To evaluate prevalence, clinical characteristics, and predictors of pain, depression,
and their impact on the quality of life (QoL) in a large neuromyelitis optica spectrum …