BACKGROUND AND PURPOSE: Diffusion-weighted (DW) MR imaging is a means to
characterize and differentiate morphologic features, including edema, necrosis, and tumor tissue, …

Objectives. This study investigated the effects of physical training on skeletal muscle
metabolism in patients with chronic heart failure. Background. Skeletal muscle metabolic …

The human body is a highly aerobic organism, in which it is necessary to match oxygen supply
at tissue levels to the metabolic demands. Along metazoan evolution, an exquisite control …

Although immune attack against central nervous system (CNS) myelin is a central feature of
multiple sclerosis (MS), its root cause is unresolved. In this report, we provide direct …

Brain tumor initiating cells (BTICs) contribute to the genesis and recurrence of gliomas. We
examined whether the microglia and macrophages that are abundant in gliomas alter BTIC …

MRI and histological studies have shown global alterations in iron levels in the brains of
patients with multiple sclerosis (MS), including increases in the iron stored by macrophages and …

Primary glial tumors of the central nervous system, most commonly glioblastoma multiforme (GBM),
are aggressive lesions with a dismal prognosis. Despite identification and isolation of …

OBJECTIVE. The purpose of our study was to describe the structural organization of the
extracellular matrix of articular cartilage of the tibial plateau and its influence on MRI appearance…

10.7554/eLife.19352.001 Seizures are often followed by sensory, cognitive or motor
impairments during the postictal phase that show striking similarity to transient hypoxic/ischemic …

Identification of remyelination is important in the evaluation of potential treatments of
demyelinating diseases such as multiple sclerosis. Local injection of lysolecithin into the brain or …