[HTML][HTML] MRI-guided thrombolysis for stroke with unknown time of onset

…, TH Cho, F Fazekas, J Fiehler… - … England Journal of …, 2018 - Mass Medical Soc
Background Under current guidelines, intravenous thrombolysis is used to treat acute stroke
only if it can be ascertained that the time since the onset of symptoms was less than 4.5 …

Results of the Stent-Protected Angioplasty versus Carotid Endarterectomy (SPACE) study to treat symptomatic stenoses at 2 years: a multinational, prospective …

…, W Hacke, M Hennerici, R Stingele, J Fiehler… - The Lancet …, 2008 - thelancet.com
Background The SPACE trial is a multinational, prospective, randomised study to test the
hypothesis that carotid artery stenting is not inferior to carotid endarterectomy for treating …

DWI-FLAIR mismatch for the identification of patients with acute ischaemic stroke within 4· 5 h of symptom onset (PRE-FLAIR): a multicentre observational study

…, DS Liebeskind, JB Fiebach, J Fiehler… - The Lancet …, 2011 - thelancet.com
Background Many patients with stroke are precluded from thrombolysis treatment because
the time from onset of their symptoms is unknown. We aimed to test whether a mismatch in …

Mechanical thrombectomy in acute ischemic stroke: Consensus statement by ESO-Karolinska Stroke Update 2014/2015, supported by ESO, ESMINT, ESNR and EAN

…, I Szikora, L Pierot, J Fiehler… - … Journal of Stroke, 2016 - journals.sagepub.com
The original version of this consensus statement on mechanical thrombectomy was approved
at the European Stroke Organisation (ESO)-Karolinska Stroke Update conference in …

Bleeding Risk Analysis in Stroke Imaging Before ThromboLysis (BRASIL) Pooled Analysis of T2*-Weighted Magnetic Resonance Imaging Data From 570 …

J Fiehler, GW Albers, JM Boulanger, L Derex, A Gass… - Stroke, 2007 - Am Heart Assoc
Background and Purpose— There has been speculation that the risk of secondary symptomatic
intracranial hemorrhage (SICH) may be increased after thrombolytic therapy in ischemic …

Clinical and angiographic risk factors for stroke and death within 30 days after carotid endarterectomy and stent-protected angioplasty: a subanalysis of the SPACE …

…, M Hartmann, PA Ringleb, J Fiehler - The Lancet …, 2008 - thelancet.com
Background Carotid endarterectomy (CEA) and carotid artery stenting (CAS) are used to
prevent ischaemic stroke in patients with stenosis of the internal carotid artery. Better …

European Stroke Organisation (ESO)-European Society for Minimally Invasive Neurological Therapy (ESMINT) guidelines on mechanical thrombectomy in acute …

…, D Toni, J De Vries, P White, J Fiehler - Journal of …, 2023 - jnis.bmj.com
Background Mechanical thrombectomy (MT) has become the cornerstone of acute ischemic
stroke management in patients with large vessel occlusion (LVO). Objective To assist …

Negative fluid‐attenuated inversion recovery imaging identifies acute ischemic stroke at 3 hours or less

…, S Siemonsen, A Krützelmann, J Fiehler… - Annals of Neurology …, 2009 - Wiley Online Library
Objective o evaluate the use of fluid‐attenuated inversion recovery (FLAIR) imaging as
surrogate marker of lesion age within the first 6 hours of ischemic stroke. Methods e analyzed …

MRI-based and CT-based thrombolytic therapy in acute stroke within and beyond established time windows: an analysis of 1210 patients

PD Schellinger, G Thomalla, J Fiehler, M Köhrmann… - Stroke, 2007 - Am Heart Assoc
Background and Purpose— The use of intravenous thrombolysis is restricted to a minority of
patients by the rigid 3-hour time window. This window may be extended by using modern …

Severe ADC decreases do not predict irreversible tissue damage in humans

J Fiehler, M Foth, T Kucinski, R Knab, M von Bezold… - Stroke, 2002 - Am Heart Assoc
Background and Purpose— A mismatch between diffusion- and perfusion-weighted MRI is
thought to define tissue at risk of infarction. This concept is based on the assumption that …