Free radicals as triggers of brain edema formation after stroke

JH Heo, SW Han, SK Lee - Free Radical Biology and Medicine, 2005 - Elsevier
Brain edema is a leading cause of death after stroke. Cytotoxic edema, which is most severe
in astrocytes, begins within a few minutes of adenosine triphosphate depletion and reflects …

[HTML][HTML] Stroke statistics in Korea: part I. Epidemiology and risk factors: a report from the korean stroke society and clinical research center for stroke

…, DW Kang, KH Yu, HJ Bae, JS Lee, JH Heo… - Journal of …, 2013 - ncbi.nlm.nih.gov
The aim of the Part I of Stroke Statistics in Korea is to summarize nationally representative
data of the epidemiology and risk factors of stroke in a single document. Every year, …

[HTML][HTML] Randomized assessment of rapid endovascular treatment of ischemic stroke

…, BW Baxter, PA Burns, H Choe, JH Heo… - … England Journal of …, 2015 - Mass Medical Soc
Background Among patients with a proximal vessel occlusion in the anterior circulation, 60
to 80% of patients die within 90 days after stroke onset or do not regain functional …

Brain microbleeds, anticoagulation, and hemorrhage risk: meta-analysis in stroke patients with AF

…, KD Flemming, T Imaizumi, V Srikanth, JH Heo… - Neurology, 2017 - AAN Enterprises
Objectives: To assess the association between cerebral microbleeds (CMBs) and future
spontaneous intracerebral hemorrhage (ICH) risk in ischemic stroke patients with nonvalvular …

Matrix metalloproteinases increase very early during experimental focal cerebral ischemia

JH Heo, J Lucero, T Abumiya… - Journal of Cerebral …, 1999 - journals.sagepub.com
Microvascular integrity is lost during focal cerebral ischemia. The degradation of the basal
lamina and extracellular matrix are, in part, responsible for the loss of vascular integrity. Matrix …

Machine learning–based model for prediction of outcomes in acute stroke

JN Heo, JG Yoon, H Park, YD Kim, HS Nam, JH Heo - Stroke, 2019 - Am Heart Assoc
Background and Purpose— The prediction of long-term outcomes in ischemic stroke patients
may be useful in treatment decisions. Machine learning techniques are being increasingly …

Efficacy and safety of nerinetide for the treatment of acute ischaemic stroke (ESCAPE-NA1): a multicentre, double-blind, randomised controlled trial

…, SJ Phillips, JL Schindler, J Thornton, S Nagel, JH Heo… - The Lancet, 2020 - thelancet.com
Background Nerinetide, an eicosapeptide that interferes with post-synaptic density protein
95, is a neuroprotectant that is effective in preclinical stroke models of ischaemia-reperfusion. …

A new subtype classification of ischemic stroke based on treatment and etiologic mechanism

…, JH Yang, HY Shin, HS Nam, BI Lee, JH Heo - European …, 2007 - karger.com
A new subtype classification of ischemic stroke was developed to reflect recent therapeutic
strategies as well as evolving concepts of stroke definitions and mechanisms. In 200 …

Yonsei Stroke Registry: analysis of 1,000 patients with acute cerebral infarctions

BI Lee, HS Nam, JH Heo, DI Kim - Cerebrovascular diseases, 2001 - karger.com
Background and Purpose: The hospital-based stroke registry is a well-established method
useful for understanding diverse clinical characteristics of stroke related to geographical, …

Different prognostic value of white blood cell subtypes in patients with acute cerebral infarction

…, JH Park, HS Lee, CM Nam, HS Nam, YD Kim, JH Heo - Atherosclerosis, 2012 - Elsevier
OBJECTIVE: We aimed to investigate the relationship of each white blood cells (WBC)
subtype with neurologic severity and outcome in acute stroke. METHODS: We included 779 …