Validating whole slide imaging for diagnostic purposes in pathology: guideline from the College of American Pathologists Pathology and Laboratory Quality Center

L Pantanowitz, JH Sinard… - … of Pathology and …, 2013 - meridian.allenpress.com
Context.—There is increasing interest in using whole slide imaging (WSI) for diagnostic
purposes (primary and/or consultation). An important consideration is whether WSI can safely …

The mesothelial keratins: a new family of cytoskeletal proteins identified in cultured mesothelial cells and nonkeratinizing epithelia

YJ Wu, LM Parker, NE Binder, MA Beckett, JH Sinard… - Cell, 1982 - cell.com
The cytoskeletal proteins of cultured normal human mesothelial cells were found to consist of
six major components, including actin, vimentin, the 40 kd keratin and the 44, 52 and 55 kd …

[HTML][HTML] Computational pathology in 2030: a Delphi study forecasting the role of AI in pathology within the next decade

…, A Karsan, M Kriegsmann, ME Salama, JH Sinard… - …, 2023 - thelancet.com
Background Artificial intelligence (AI) is rapidly fuelling a fundamental transformation in the
practice of pathology. However, clinical integration remains challenging, with no AI …

Computational pathology: a path ahead

…, JR Gilbertson, JH Sinard… - … of pathology & …, 2016 - meridian.allenpress.com
Context We define the scope and needs within the new discipline of computational pathology,
a discipline critical to the future of both the practice of pathology and, more broadly, …

[HTML][HTML] Immune checkpoint inhibitor–associated pericarditis

…, J Zugazagoitia, JH Sinard… - Journal of Thoracic …, 2019 - Elsevier
Side effects of immune checkpoint inhibitors, termed immune-related adverse events, are
relatively common, but immune checkpoint inhibitor–mediated cardiotoxicities are rare; …

Immunohistochemical distinction of ocular sebaceous carcinoma from basal cell and squamous cell carcinoma

JH Sinard - Archives of ophthalmology, 1999 - jamanetwork.com
Background Diagnosis of sebaceous carcinoma of the periorbital region is often delayed.
Clinically, this lesion can mimic several inflammatory disorders. Histopathologically, it can …

Factors affecting autopsy rates, autopsy request rates, and autopsy findings at a large academic medical center

JH Sinard - Experimental and molecular pathology, 2001 - Elsevier
Autopsy rates continue to decline in the United States. To assess the impact of various
objective factors (time of death, day of death, age at death, patient gender, clinical service, and …

The mechanism of assembly of Acanthamoeba myosin-II minifilaments: minifilaments assemble by three successive dimerization steps.

JH Sinard, WF Stafford, TD Pollard - The Journal of cell biology, 1989 - rupress.org
We used 90 degrees light scattering, analytical ultracentrifugation, and electron microscopy
to deduce that Acanthamoeba myosin-II minifilaments, composed of eight molecules each, …

Reduced alpha-catenin and E-cadherin expression in breast cancer.

DL Rimm, JH Sinard, JS Morrow - Laboratory investigation; a journal …, 1995 - europepmc.org
Background The expression of the homotypic cell adhesion protein, E-cadherin, is reduced
in many types of cancer. The loss of this protein may be associated with metastasis because …

Pathology informatics essentials for residents: a flexible informatics curriculum linked to accreditation council for graduate medical education milestones (a secondary …

…, DS Karcher, JH Harrison Jr, JH Sinard… - Academic …, 2016 - journals.sagepub.com
Context: Recognition of the importance of informatics to the practice of pathology has surged.
Training residents in pathology informatics has been a daunting task for most residency …