The Effects of Changes in PaCO2 Cerebral Blood Volume, Blood Flow, and Vascular Mean Transit Time

RL Grubb Jr, ME Raichle, JO Eichling… - Stroke, 1974 - Am Heart Assoc
The relationships between cerebral blood volume (CBV), cerebral blood flow (CBF), and the
cerebral vascular mean transit time (t v ) during acute changes in the PaCO 2 over a range …

Central noradrenergic regulation of cerebral blood flow and vascular permeability.

…, BK Hartman, JO Eichling… - Proceedings of the …, 1975 - National Acad Sciences
Anatomical studies employing the immunofluorescence localization of dopamine-beta-hydroxylase
[= dopamine beta-monooxygenase; 3,4-dihydroxyphenylethylamine, ascorbate:…

Correlation between regional cerebral blood flow and oxidative metabolism: in vivo studies in man

…, RL Grubb, MH Gado, JO Eichling… - Archives of …, 1976 - jamanetwork.com
• To test the hypothesis that regional cerebral blood flow (rCBF) is normally regulated by
regional metabolic activity, rCBF and the regional cerebral metabolic rate for oxygen (rCMRO 2 …

Effects of subarachnoid hemorrhage on cerebral blood volume, blood flow, and oxygen utilization in humans

RL Grubb, ME Raichle, JO Eichling, MH Gado - Journal of neurosurgery, 1977 - thejns.org
✓ Forty-five studies of regional cerebral blood volume (rCBV), regional cerebral blood flow (rCBF),
and regional cerebral oxygen utilization (rCMRO 2 ) were performed in 30 patients …

Evidence of the limitations of water as a freely diffusible tracer in brain of the rhesus monkey

JO Eichling, ME Raichle, RL Grubb Jr… - Circulation …, 1974 - Am Heart Assoc
The extraction of 15 O-labeled water by the brain during a single capillary transit was studied
in vivo in 20 adult rhesus monkeys by external detection of the time course of the tracer …

Blood-brain barrier permeability of 11C-labeled alcohols and 15O-labeled water

ME Raichle, JO Eichling… - … Journal of …, 1976 - journals.physiology.org
The extraction of 11C-labeled methanol, ethanol, and isopropanol, as well as 15O-labeled
water by the brain during a single capillary transit, was studied in vivo in six adult rhesus …

The measure in vivo of regional cerebral oxygen utilization by means of oxyhemoglobin labeled with radioactive oxygen-15

MM Ter-Pogossian, JO Eichling… - The Journal of …, 1970 - Am Soc Clin Investig
Regional cerebral oxygen utilization rate is measured in vivo by the following method: A small
volume of blood with radioactive oxygen-15-tagged hemoglobin is rapidly injected into the …

Radiation exposure from outpatient radioactive iodine (131I) therapy for thyroid carcinoma

PW Grigsby, BA Siegel, S Baker, JO Eichling - Jama, 2000 - jamanetwork.com
ContextIn May 1997, the US Nuclear Regulatory Commission (NRC) revised its patient
release regulations, allowing for outpatient administration of larger activities of sodium iodide …

Measurement of regional cerebral blood volume by emission tomography

…, ME Raichle, CS Higgins, JO Eichling - Annals of Neurology …, 1978 - Wiley Online Library
The technique of positron emission tomography was used to measure cerebral blood volume
(CBV) in 10 normal right‐handed human volunteers following inhalation of trace quantities …

In vivo determination of cerebral blood volume with radioactive oxygen-15 in the monkey.

JO Eichling, ME Raichle, RL Grubb Jr… - Circulation …, 1975 - Am Heart Assoc
A method for the in vivo determination of cerebral blood volume was tested in 15 adult
rhesus monkeys. The technique utilized external residue detection and required the serial …