Parkinson’s disease (PD) is characterized by a range of motor symptoms. Besides the cardinal
symptoms (akinesia and bradykinesia, tremor and rigidity), PD patients show additional …

The cerebellum has been considered for a long time to play a role solely in motor coordination.
However, studies over the past two decades have shown that the cerebellum also plays …

Mast cells (MC) are a bone marrow-derived, long-lived, heterogeneous cellular population
that function both as positive and negative regulators of immune responses. They are …

BACKGROUND AND PURPOSE: Conventional MR imaging findings of human brain
development are thought to result from decreasing water content, increasing macromolecular …

Background. Septicemia is a major antecedent of morbidity and mortality in very low birth
weight (501-to 1500-g) infants. Our purpose was to determine prospectively the incidence, …

Stress-inducible MICA, a distant homolog of major histocompatibility complex (MHC) class I,
functions as an antigen for γδ T cells and is frequently expressed in epithelial tumors. A …

The protein HLA-E is a non-classical major histocompatibility complex (MHC) molecule of
limited sequence variability. Its expression on the cell surface is regulated by the binding of …

Many immune receptors are composed of separate ligand-binding and signal-transducing
subunits. In natural killer (NK) and T cells, DAP10 was identified as a cell surface adaptor …

THE membrane antigen B7/BB1 (refs 1, 2) is expressed on activated B cells, macrophages
and dendritic cells, and binds to a counter-receptor, CD28, expressed on T lymphocytes and …

Natural killer (NK) cells express cell-surface receptors of the immunoglobulin and C-type lectin
superfamilies that recognize major histocompatibility complex (MHC) class I peptides and …