BACKGROUND AND PURPOSE: Subacute necrotizing encephalomyelopathy, or Leigh
syndrome (LS), is a progressive neurodegenerative disorder characterized by symmetrical …

Pelizaeus‐Merzbacher disease (PMD) is an X‐linked disorder characterized by dysmyelination
of the central nervous system (CNS) caused by mutations involving the proteolipid …

Objective: To investigate the clinical and pathologic characteristics of primary encephalopathy
caused by nontyphoidal salmonellosis (NTS). Methods: Case records of six Japanese …

The importance of an acute encephalopathy associated with nontyphoidal salmonellosis has
recently been recognized, but the disease entity has been poorly established. In this study, …

Children who develop clinical hypothyroidism in early childhood have various degrees of
irreversible brain damage, albeit less severe than cases detected by neonatal screening test …

A factor inhibiting cell-free protein synthesis was purified from Salmonella enteritidis cell
lysate by sequential ammonium sulfate precipitation, chromatography on anion exchange and …

Narcolepsy is characterized by excessive daytime sleepiness (EDS), cataplexy and other
abnormal manifestations of REM sleep. Recently, it was discovered that the pathophysiology of …

Narcolepsy and other sleep disorders are underrecognized in children; therefore, the final
diagnosis and initiation of treatment is often delayed. This is due to the fact that the expression …

Iodine deficiency interferes with the prenatal and postnatal neurointellectual development of
children through maternal, fetal and neonatal hypothyroxinemia. The purpose of this review …

A tight association (90–95%) between human narcolepsy-cataplexy and hypocretin orexin
deficiency has recently been revealed ( 1 – 8 ). Hypocretins are hypothalamic neuropeptides …