Reversal of clinical features of Hurler's disease and biochemical improvement after treatment by bone-marrow transplantation

…, DCO James, K Hugh-Jones, N Byrom, K Henry… - The Lancet, 1981 - Elsevier
A one-year-old boy with type IH mucopoly saccharidosis (Hurler's disease) was given a
bone-marrow transplant (BMT) from his mother in an attempt to replace the deficient enzyme, …

Bone marrow transplantation for Sanfilippo disease type B

…, M New, C Pot‐Mees, K HughJones - Journal of inherited …, 1992 - Wiley Online Library
Allogeneic bone marrow transplantation was performed on twins with Sanfilippo B disease.
They were the first two patients with this disorder to undergo the procedure. There was …

Treatment of Niemann-Pick disease type B by allogeneic bone marrow transplantation.

…, NM O'Donnell, BS Coulter, K Hugh-Jones - Br Med J (Clin Res …, 1987 - bmj.com
Allogenic bone marrow transplantation was carried out on a 3 year old girl with Niemann-Pick
disease type B. Successful engraftment was achieved, and nine months after the …

Beneficial effect of pre-transplant splenectomy on displacement bone marrow transplantation for Gaucher's syndrome

JR Hobbs, PJ Shaw, KH Jones, I Lindsay, M Hancock - The Lancet, 1987 - Elsevier
2 patients with fast and 4 with medium varieties of Gaucher's syndrome were treated by
displacement bone marrow transplantation to install a donor enzyme factory for life. …

Immunomodulatory therapy to achieve maximum efficacy: doses, monitoring, compliance, and self-infusion at home

M Lucas, K Hugh-Jones, A Welby, S Misbah… - Journal of clinical …, 2010 - Springer
… Clinical data from patients with autoimmune diseases who were seen in the Department
of Clinical Immunology for more than 17 years were reviewed by a physician (K. Hugh-Jones) …

Class‐and subclass‐specific pneumococcal antibody levels and response to immunization after bone marrow transplantation

…, A Vellodi, ES Jurges, K HughJones - Clinical & …, 1992 - Wiley Online Library
Immunoglobulin class‐ and subclass‐specific antibodies to a polyvalent pneumococcal
capsular polysaccharide vaccine (Pneumovax II) were measured before and after immunization …

Cyclosporin A as prophylaxis against graft-versus-host disease in 36 patients.

…, DV Joss, R Joshi, P Pendharkar, K Hugh-Jones - Br Med J (Clin Res …, 1982 - bmj.com
Oral cyclosporin A was used as prophylaxis against graft-versus-host disease in (a) 31
patients with acute leukaemia or aplastic anaemia given transplants of HLA-matched bone …

Heterogeneity of biochemical, clinical and immunological parameters in severe combined immunodeficiency due to adenosine deaminase deficiency.

G Morgan, RJ Levinsky, K Hugh-Jones… - Clinical and …, 1987 - ncbi.nlm.nih.gov
There was considerable heterogeneity of the biochemical, clinical and immunological
findings in 12 patients and two fetuses from 16 kindreds affected by severe combined …

Exploring the substellar temperature regime down to∼ 550 K

B Burningham, DJ Pinfield, SK Leggett… - Monthly Notices of …, 2008 - academic.oup.com
… The NIR to mid-IR spectral energy distribution of ULAS1335 further supports T eff < 600 K,
and we estimate T eff ∼ 550–600 K for ULAS1335. We estimate that ULAS1335 has an age of …

Engraftment rates related to busulphan and cyclophosphamide dosages for displacement bone marrow transplants in fifty children.

JR Hobbs, K Hugh-Jones, PJ Shaw… - Bone Marrow …, 1986 - europepmc.org
The use of busulphan and cyclophosphamide permitted engraftment in 44 of 49 children
receiving'displacement'bone marrow transplants. Three patients who received T-cell-depleted …