Concurrent radiotherapy and ipilimumab immunotherapy for patients with melanoma
Ipilimumab and radiotherapy are commonly used to treat unresectable and metastatic
melanoma. Results from preclinical studies and case reports suggest a biologic interaction …
melanoma. Results from preclinical studies and case reports suggest a biologic interaction …
[HTML][HTML] A comparative encyclopedia of DNA elements in the mouse genome
…, KR Rosenbloom, B Lacerda de Sousa, K Beal… - Nature, 2014 - nature.com
The laboratory mouse shares the majority of its protein-coding genes with humans, making
it the premier model organism in biomedical research, yet the two mammals differ in …
it the premier model organism in biomedical research, yet the two mammals differ in …
Ensembl 2014
Ensembl ( http://www.ensembl.org ) creates tools and data resources to facilitate genomic
analysis in chordate species with an emphasis on human, major vertebrate model organisms …
analysis in chordate species with an emphasis on human, major vertebrate model organisms …
Ensembl 2015
Ensembl ( http://www.ensembl.org ) is a genomic interpretation system providing the most up-to-date
annotations, querying tools and access methods for chordates and key model …
annotations, querying tools and access methods for chordates and key model …
[PDF][PDF] Improving cancer treatment via mathematical modeling: surmounting the challenges is worth the effort
F Michor, K Beal - Cell, 2015 - cell.com
Drug delivery schedules are key factors in the efficacy of cancer therapies, and mathematical
modeling of population dynamics and treatment responses can be applied to identify better …
modeling of population dynamics and treatment responses can be applied to identify better …
[HTML][HTML] A high-resolution map of human evolutionary constraint using 29 mammals
The comparison of related genomes has emerged as a powerful lens for genome interpretation.
Here we report the sequencing and comparative analysis of 29 eutherian genomes. We …
Here we report the sequencing and comparative analysis of 29 eutherian genomes. We …
The staden package, 1998
R Staden, KF Beal, JK Bonfield - Bioinformatics methods and protocols, 1999 - Springer
For several years we have been concentrating on developing methods for large-scale
sequencing projects and the resulting software is used in many major laboratories and genome …
sequencing projects and the resulting software is used in many major laboratories and genome …
Ensembl 2012
The Ensembl project ( http://www.ensembl.org ) provides genome resources for chordate
genomes with a particular focus on human genome data as well as data for key model …
genomes with a particular focus on human genome data as well as data for key model …
Ensembl 2013
The Ensembl project ( http://www.ensembl.org ) provides genome information for sequenced
chordate genomes with a particular focus on human, mouse, zebrafish and rat. Our …
chordate genomes with a particular focus on human, mouse, zebrafish and rat. Our …
Ensembl 2009
…, BL Aken, S Ayling, B Ballester, K Beal… - Nucleic acids …, 2009 - academic.oup.com
The Ensembl project ( http://www.ensembl.org ) is a comprehensive genome information
system featuring an integrated set of genome annotation, databases, and other information for …
system featuring an integrated set of genome annotation, databases, and other information for …