User profiles for K. Landheer
 | Karl LandheerRegeneron Pharmaceuticals Verified email at regeneron.com Cited by 690 |
[HTML][HTML] Quantifying the metabolic signature of multiple sclerosis by in vivo proton magnetic resonance spectroscopy: current challenges and future outlook in the …
Proton magnetic resonance spectroscopy ( 1 H-MRS) offers a growing variety of methods
for querying potential diagnostic biomarkers of multiple sclerosis in living central nervous …
for querying potential diagnostic biomarkers of multiple sclerosis in living central nervous …
Advanced single voxel 1H magnetic resonance spectroscopy techniques in humans: Experts' consensus recommendations
Conventional proton MRS has been successfully utilized to noninvasively assess tissue
biochemistry in conditions that result in large changes in metabolite levels. For more challenging …
biochemistry in conditions that result in large changes in metabolite levels. For more challenging …
[HTML][HTML] Multiancestry exome sequencing reveals INHBE mutations associated with favorable fat distribution and protection from diabetes
Body fat distribution is a major, heritable risk factor for cardiometabolic disease, independent
of overall adiposity. Using exome-sequencing in 618,375 individuals (including 160,058 …
of overall adiposity. Using exome-sequencing in 618,375 individuals (including 160,058 …
Theoretical description of modern 1H in Vivo magnetic resonance spectroscopic pulse sequences
K Landheer, RF Schulte, MS Treacy… - Journal of Magnetic …, 2020 - Wiley Online Library
This article reviews the most commonly used modern sequences designed to confront the
two major challenges of in vivo magnetic resonance spectroscopy (MRS): spatial localization …
two major challenges of in vivo magnetic resonance spectroscopy (MRS): spatial localization …
Across‐vendor standardization of semi‐LASER for single‐voxel MRS at 3T
The semi‐adiabatic localization by adiabatic selective refocusing (sLASER) sequence
provides single‐shot full intensity signal with clean localization and minimal chemical shift …
provides single‐shot full intensity signal with clean localization and minimal chemical shift …
Magnetic resonance Spectrum simulator (MARSS), a novel software package for fast and computationally efficient basis set simulation
The aim of this study was to develop a novel software platform for the simulation of magnetic
resonance spin systems, capable of simulating a large number of spatial points (128 3 ) for …
resonance spin systems, capable of simulating a large number of spatial points (128 3 ) for …
[HTML][HTML] INSPECTOR: free software for magnetic resonance spectroscopy data inspection, processing, simulation and analysis
In vivo magnetic resonance spectroscopy (MRS) is a powerful tool for biomedical research
and clinical diagnostics, allowing for non-invasive measurement and analysis of small …
and clinical diagnostics, allowing for non-invasive measurement and analysis of small …
Low-Energy Electron-Induced Decomposition and Reactions of Adsorbed Tetrakis(trifluorophosphine)platinum [Pt(PF3)4]
K Landheer, SG Rosenberg, L Bernau… - The Journal of …, 2011 - ACS Publications
… Pt foil at 20–30 K (bottom spectrum). HREEL spectra at the top show the changes that occur
when the Pt(PF 3 ) 4 adlayer is annealed to 140 K and then exposed to 500 eV electrons. …
when the Pt(PF 3 ) 4 adlayer is annealed to 140 K and then exposed to 500 eV electrons. …
[HTML][HTML] Frequency drift in MR spectroscopy at 3T
Purpose Heating of gradient coils and passive shim components is a common cause of
instability in the B 0 field, especially when gradient intensive sequences are used. The aim of the …
instability in the B 0 field, especially when gradient intensive sequences are used. The aim of the …
Concentration and effective T2 relaxation times of macromolecules at 3T
K Landheer, M Gajdošík, M Treacy… - Magnetic Resonance in …, 2020 - Wiley Online Library
Purpose We aimed to investigate the concentration and effective T 2 relaxation time of
macromolecules assessed with an ultra‐short TE sLASER sequence in 2 brain regions, the …
macromolecules assessed with an ultra‐short TE sLASER sequence in 2 brain regions, the …