User profiles for K. Ogasawara

Ken Ogasawara

- Verified email at bms.com - Cited by 4068

Keiichi Ogasawara

- Verified email at swri.edu - Cited by 871

IRF family of transcription factors as regulators of host defense

T Taniguchi, K Ogasawara, A Takaoka… - Annual review of …, 2001 - annualreviews.org
… II molecules (K Ogasawara. T Taniguchi, unpublished data). These studies may provide a
new link between the IFN-α/β system and the CD8 + T cell-mediated adaptive immune system. …

NK cells in innate immunity

JA Hamerman, K Ogasawara, LL Lanier - Current opinion in immunology, 2005 - Elsevier
NK cells have an important role in innate immune responses, particularly in anti-viral
immunity. Recent studies have revealed a molecular basis for NK cell recognition of virus-infected …

[HTML][HTML] Interstellar mapping and acceleration probe (IMAP): A new NASA mission

…, D Mitchell, E Moebius, K Ogasawara… - Space science …, 2018 - Springer
The Interstellar Mapping and Acceleration Probe (IMAP) is a revolutionary mission that
simultaneously investigates two of the most important overarching issues in Heliophysics today: …

Lisocabtagene maraleucel for patients with relapsed or refractory large B-cell lymphomas (TRANSCEND NHL 001): a multicentre seamless design study

…, A Kostic, M Mallaney, K Ogasawara, K Newhall… - The Lancet, 2020 - thelancet.com
Background Lisocabtagene maraleucel (liso-cel) is an autologous, CD19-directed, chimeric
antigen receptor (CAR) T-cell product. We aimed to assess the activity and safety of liso-cel …

[HTML][HTML] In vitro and in vivo characterization of new swine-origin H1N1 influenza viruses

…, M Ozawa, G Neumann, J Gern, H Kida, K Ogasawara… - Nature, 2009 - nature.com
… Kazumasa Ogasawara … We thank K. Wells for editing the manuscript, and M. McGregor,
R. … Yasushi Itoh, Hirohito Ishigaki, Misako Nakayama & Kazumasa Ogasawara

T-cell-mediated regulation of osteoclastogenesis by signalling cross-talk between RANKL and IFN-γ

…, K Ogasawara, S Hida, T Chiba, S Murata, K Sato… - Nature, 2000 - nature.com
Bone resorption is regulated by the immune system 1 , 2 , where T-cell expression of RANKL
(receptor activator of nuclear factor (NF)-κB ligand), a member of the tumour-necrosis factor …

Mutations of optineurin in amyotrophic lateral sclerosis

…, M Aoki, A Kawata, T Hirai, T Kato, K Ogasawara… - Nature, 2010 - nature.com
… f–k, Round hyaline inclusions of subjects with SALS (f, i) are immunolabelled with anti-OPTN-C …
Miki and K. Noda for providing some DNA samples and clinical information. This paper is …

[PDF][PDF] Distinct and essential roles of transcription factors IRF-3 and IRF-7 in response to viruses for IFN-α/β gene induction

…, H Suemori, N Hata, M Asagiri, K Ogasawara, K Nakao… - Immunity, 2000 - cell.com
Induction of the interferon (IFN)-α/β gene transcription in virus-infected cells is an event central
to innate immunity. Mice lacking the transcription factor IRF-3 are more vulnerable to virus …

Lisocabtagene maraleucel versus standard of care with salvage chemotherapy followed by autologous stem cell transplantation as second-line treatment in patients …

…, S Montheard, A Previtali, L Stepan, K Ogasawara… - The Lancet, 2022 - thelancet.com
Background Patients with large B-cell lymphoma (LBCL) primary refractory to or relapsed
within 12 months of first-line therapy are at high risk for poor outcomes with current standard of …

Requirement for IRF-1 in the microenvironment supporting development of natural killer cells

K Ogasawara, S Hida, N Azimi, Y Tagaya, T Sato… - Nature, 1998 - nature.com
Natural killer (NK) cells are critical for both innate and adaptive immunity 1 , 2 . The
development of NK cells requires interactions between their progenitors and the bone-marrow …