User profiles for K. Scheffler

Klaus Scheffler

- Verified email at tuebingen.mpg.de - Cited by 22059

Konrad Scheffler

- Verified email at illumina.com - Cited by 8631

Principles and applications of balanced SSFP techniques

K Scheffler, S Lehnhardt - European radiology, 2003 - Springer
… For simplicity we assume that we are just encoding the center line of k-space, which
means that the phase-… A pictorial description of rapid SSFP imaging is given by Scheffler [4]. …

Fundamentals of balanced steady state free precession MRI

O Bieri, K Scheffler - Journal of Magnetic Resonance Imaging, 2013 - Wiley Online Library
… Analytical solutions to the transient response of SSFP were first derived by Scheffler 7
and have been further adapted to include off-resonance effects by Ganter 8. As noted by …

Assembly and positioning of the oocyte meiotic spindle

B Mogessie, K Scheffler, M Schuh - Annual review of cell and …, 2018 - annualreviews.org
… The observation that chromosomes frequently lag when actin is depolymerized in
oocytes therefore supports our model of actin-dependent k-fiber formation (Figure 3). …

[HTML][HTML] Detecting individual sites subject to episodic diversifying selection

…, JO Wertheim, S Moola, T Weighill, K Scheffler… - PLoS …, 2012 - journals.plos.org
The imprint of natural selection on protein coding genes is often difficult to identify because
selection is frequently transient or episodic, ie it affects only a subset of lineages. Existing …

FUBAR: a fast, unconstrained bayesian approximation for inferring selection

…, SL Kosakovsky Pond, K Scheffler - Molecular biology …, 2013 - academic.oup.com
… We begin in an initial state based on relative cumulative weights assigned to each grid point
derived from the precomputed conditional likelihoods at each site k: forumla ⁠, where C k = …

Strelka2: fast and accurate calling of germline and somatic variants

S Kim, K Scheffler, AL Halpern, MA Bekritsky, E Noh… - Nature …, 2018 - nature.com
… Here, d k and q k are the kth base in d and the corresponding probability of the call being …
), respectively, and a k is the base in h to which d k has been aligned or, if d k is aligned to an …

Less is more: an adaptive branch-site random effects model for efficient detection of episodic diversifying selection

…, S Weaver, B Murrell, K Scheffler… - Molecular biology …, 2015 - academic.oup.com
… The range of possible parameter values for ω k < K b b is constrained to [ 0 , 1 ] ⁠, whereas
ω k = K b b can take on any value in [ 0 , ∞ ) ⁠. Changing the model to enforce the absence …

Gene-wide identification of episodic selection

…, DP Martin, DM Smith, K Scheffler… - Molecular biology …, 2015 - academic.oup.com
We present BUSTED, a new approach to identifying gene-wide evidence of episodic
positive selection, where the non-synonymous substitution rate is transiently greater than the …

RELAX: detecting relaxed selection in a phylogenetic framework

…, SL Kosakovsky Pond, K Scheffler - Molecular biology …, 2015 - academic.oup.com
… model in which k is a free parameter. When the introduction of k produces a statistically …
test branches is intensified (k > 1) or relaxed (k < 1) compared with background branches. …

Processing of temporal unpredictability in human and animal amygdala

…, F Di Salle, WJ Perrig, K Scheffler… - Journal of …, 2007 - Soc Neuroscience
The amygdala has been studied extensively for its critical role in associative fear conditioning
in animals and humans. Noxious stimuli, such as those used for fear conditioning, are …