A comparative study of deformable contour methods on medical image segmentation

…, B Everding, X Wang, CY Han, KL Weiss… - Image and vision …, 2008 - Elsevier
… The “gold standard” segmentations shown beside the test images were selected pixel-by-pixel
by a board-certified radiologist (the 6th author, KL Weiss), which were used as the expert …

[HTML][HTML] Covalent narlaprevir-and boceprevir-derived hybrid inhibitors of SARS-CoV-2 main protease

DW Kneller, H Li, G Phillips, KL Weiss, Q Zhang… - Nature …, 2022 - nature.com
Emerging SARS-CoV-2 variants continue to threaten the effectiveness of COVID-19 vaccines,
and small-molecule antivirals can provide an important therapeutic treatment option. The …

Neurosarcoidosis

EE Lower, KL Weiss - Clinics in chest medicine, 2008 - Elsevier
Although neurosarcoidosis seems to occur in only 5% to 10% of patients who have sarcoidosis,
it may lead to significant complications. The diagnosis of neurosarcoidosis usually relies …

Abnormal frontal white matter tracts in bipolar disorder: a diffusion tensor imaging study

…, V Schmithorst, M Wilke, KL Weiss… - Bipolar …, 2004 - Wiley Online Library
Objectives: Prefrontal white matter has been hypothesized to be integral to the pathophysiology
of bipolar disorder. Recent morphometric studies however, have not observed changes …

[HTML][HTML] Unusual zwitterionic catalytic site of SARS–CoV-2 main protease revealed by neutron crystallography

DW Kneller, G Phillips, KL Weiss, S Pant… - Journal of Biological …, 2020 - ASBMB
The main protease (3CL M pro ) from SARS–CoV-2, the etiological agent of COVID-19, is
an essential enzyme for viral replication. 3CL M pro possesses an unusual catalytic dyad …

[PDF][PDF] Dynamics of protein and its hydration water: neutron scattering studies on fully deuterated GFP

…, H O'Neill, L Hong, M Tyagi, G Ehlers, KL Weiss… - Biophysical journal, 2012 - cell.com
We present a detailed analysis of the picosecond-to-nanosecond motions of green fluorescent
protein (GFP) and its hydration water using neutron scattering spectroscopy and hydrogen…

Comparison of vasoconstrictors for functional endoscopic sinus surgery in children

…, JB Gunter, RP Lusk, HR Muntz, KL Weiss - The …, 1992 - Wiley Online Library
Three different vasoconstricting agents were evaluated during functional endoscopic sinus
surgery (FESS) in 57 children. Oxymetazoline hydrochloride 0.05%, phenylephrine …

Calcium-dependent regulation of the voltage-gated sodium channel hH1: intrinsic and extrinsic sensors use a common molecular switch

VN Shah, TL Wingo, KL Weiss… - Proceedings of the …, 2006 - National Acad Sciences
The function of the human cardiac voltage-gated sodium channel Na V 1.5 (hH1) is regulated
in part by binding of calcium to an EF hand in the C-terminal cytoplasmic domain. hH1 is …

The Bio-SANS instrument at the high flux isotope reactor of Oak Ridge National Laboratory

WT Heller, VS Urban, GW Lynn, KL Weiss… - Journal of Applied …, 2014 - scripts.iucr.org
Small-angle neutron scattering (SANS) is a powerful tool for characterizing complex
disordered materials, including biological materials. The Bio-SANS instrument of the High Flux …

Neuro-ophthalmic sarcoidosis

RP Baughman, KL Weiss, KC Golnik - Eye and brain, 2012 - Taylor & Francis
Neuro-ophthalmic disease occurs in about a third of patients with neurosarcoidosis. Optic
nerve involvement is the most common manifestation, but other cranial nerves and the optic …