Background Stroke thrombolysis with alteplase is currently recommended 0–4·5 h after
stroke onset. We aimed to determine whether perfusion imaging can identify patients with …

Background CT perfusion (CTP) and diffusion or perfusion MRI might assist patient selection
for endovascular thrombectomy. We aimed to establish whether imaging assessments of …

Background Intracerebral haemorrhage growth is associated with poor clinical outcome and
is a therapeutic target for improving outcome. We aimed to determine the absolute risk and …

Background Whether intravenous tissue plasminogen activator (alteplase) is effective beyond
3 h after onset of acute ischaemic stroke is unclear. We aimed to test whether alteplase …

Background and Purpose— Hyperglycemia at the time of ischemic stroke is associated with
increased mortality and morbidity. Animal studies suggest that infarct expansion may be …

Background and Purpose— Acute blood pressure (BP) reduction aimed at attenuation of
intracerebral hemorrhage (ICH) expansion might also compromise cerebral blood flow (CBF). …

Background and Purpose— The Echoplanar Imaging Thrombolysis Evaluation Trial (EPITHET)
tests the hypothesis that perfusion-weighted imaging (PWI)–diffusion-weighted imaging (…

… Butcher … Butcher … Dr Butcher is supported by fellowships from the Canadian Institute
of Health Research and the Alberta Heritage Foundation for Medical Research. …

Importance The relative rates of detection of atrial fibrillation (AF) or atrial flutter from evaluating
patients with prolonged electrocardiographic monitoring with an external loop recorder …

… Dr Butcher has received speaker's honoraria from Octapharma and served on advisory
boards for Bayer Canada, Boehringer Ingelheim, and Pfizer/BMS. Dr Poon has served on …