MRI is commonly used to determine the location and extent of cerebral gliomas. We investigated
whether the diagnostic accuracy of MRI could be improved by the additional use of PET …

As the applications of metabolic imaging are expanding, radiolabeled amino acids may
gain increased clinical interest. This review first describes the basic aspects of amino acid …

These joint practice guidelines, or procedure standards, were developed collaboratively by
the European Association of Nuclear Medicine (EANM), the Society of Nuclear Medicine and …

O-(2-[ 18 F]fluoroethyl)-l-tyrosine (FET) is a promising tracer for PET that has demonstrated
convincing results especially in the diagnostics of brain tumors. In contrast to other …

Despite the fact that MRI has evolved to become the standard method for diagnosis and
monitoring of patients with brain tumours, conventional MRI sequences have two key limitations: …

In 23 patients with moderate to severe Huntington's disease (HD) and 21 normal volunteers,
the regional cerebral metabolic rate of glucose consumption (rCMRGlc) was measured in …

Purpose The follow-up of glioblastoma patients after radiochemotherapy with conventional
MRI can be difficult since reactive alterations to the blood–brain barrier with contrast …

Using positron emission tomography (PET), measurements of the regional cerebral metabolic
rate of glucose (rCMRGlc) are able to delineate cerebral metabolic responses to external …

The assessment of treatment response in glioblastoma is difficult with MRI because reactive
blood–brain barrier alterations with contrast enhancement can mimic tumor progression. In …

The transport mechanisms of O-(2-[ 18 F]fluoroethyl)-L-tyrosine (FET) and 2-[ 18 F]fluoro-L-tyrosine
(FTyr) were compared to those of [ 3 H]-Methyl-L-methionine (MET) in F98 rat glioma …