[HTML][HTML] BANK regulates BCR‐induced calcium mobilization by promoting tyrosine phosphorylation of IP3 receptor
B‐cell activation mediated through the antigen receptor is dependent on activation of protein
tyrosine kinases (PTKs) such as Lyn and Syk and subsequent phosphorylation of various …
tyrosine kinases (PTKs) such as Lyn and Syk and subsequent phosphorylation of various …
Depletion of mammalian CCR4b deadenylase triggers elevation of the p27Kip1 mRNA level and impairs cell growth
…, T Suzuki, T Nakamura, K Yokoyama… - … and cellular biology, 2007 - Am Soc Microbiol
The stability of mRNA influences the abundance of cellular transcripts and proteins.
Deadenylases play critical roles in mRNA turnover and thus are important for the regulation of …
Deadenylases play critical roles in mRNA turnover and thus are important for the regulation of …
[HTML][HTML] Humoral response against host-mimetic homologous epitopes of Mycobacterium avium subsp. paratuberculosis in Japanese multiple sclerosis patients
Several works have demonstrated the existence of a link between Mycobacterium avium
subsp. paratuberculosis (MAP) and MS in Italy. In this study, we analyzed the serology of MAP …
subsp. paratuberculosis (MAP) and MS in Italy. In this study, we analyzed the serology of MAP …
Safety and efficacy of rozanolixizumab in patients with generalised myasthenia gravis (MycarinG): a randomised, double-blind, placebo-controlled, adaptive phase 3 …
…, T Hatano, K Oikoshi, K Yokoyama… - The Lancet …, 2023 - thelancet.com
Background Generalised myasthenia gravis is a chronic, unpredictable, and debilitating
autoimmune disease. New treatments for this disease are needed because conventional …
autoimmune disease. New treatments for this disease are needed because conventional …
Autoimmune targets of heart and skeletal muscles in myasthenia gravis
…, M Motomura, S Matsubara, K Yokoyama… - Archives of …, 2009 - jamanetwork.com
Objective To investigate the clinical, histological, and immunological features of patients
with myasthenia gravis (MG) who also developed myocarditis and/or myositis. Design …
with myasthenia gravis (MG) who also developed myocarditis and/or myositis. Design …
[HTML][HTML] Differences of behavioral and psychological symptoms of dementia in disease severity in four major dementias
…, T Matsumoto, T Mori, T Kashibayashi, K Yokoyama… - PloS one, 2016 - journals.plos.org
Background/Aims Behavioral and psychological symptoms of dementia (BPSDs) negatively
impact the prognosis of dementia patients and increase caregiver distress. The aims of this …
impact the prognosis of dementia patients and increase caregiver distress. The aims of this …
Microarray analysis identifies an aberrant expression of apoptosis and DNA damage-regulatory genes in multiple sclerosis
…, M Kawai, S Kikuchi, K Nomura, K Yokoyama… - Neurobiology of …, 2005 - Elsevier
To clarify the molecular mechanisms underlying multiple sclerosis (MS)-promoting autoimmune
process, we have investigated a comprehensive gene expression profile of T cell and …
process, we have investigated a comprehensive gene expression profile of T cell and …
[HTML][HTML] Apathy/depression, but not subjective fatigue, is related with cognitive dysfunction in patients with multiple sclerosis
…, T Yamamura, F Yoshii, J Kira, S Nakane, K Yokoyama… - BMC neurology, 2014 - Springer
Background Cognitive impairment could affect quality of life for patients with multiple sclerosis
(MS), and cognitive function may be correlated with several factors such as depression …
(MS), and cognitive function may be correlated with several factors such as depression …
[HTML][HTML] Plasmablasts as migratory IgG-producing cells in the pathogenesis of neuromyelitis optica
…, T Matsuoka, M Nakamura, H Kishida, K Yokoyama… - PloS one, 2013 - journals.plos.org
Neuromyelitis optica (NMO) is an inflammatory disease characterized by recurrent attacks of
optic neuritis and myelitis. It is generally accepted that autoantibodies against aquaporin 4 …
optic neuritis and myelitis. It is generally accepted that autoantibodies against aquaporin 4 …
Diffusional kurtosis imaging of normal-appearing white matter in multiple sclerosis: preliminary clinical experience
M Yoshida, M Hori, K Yokoyama, I Fukunaga… - Japanese journal of …, 2013 - Springer
Purpose We evaluated diffusional changes in normal-appearing white matter (NAWM) regions
remote from multiple sclerosis (MS) plaques by using diffusional kurtosis imaging (DKI) to …
remote from multiple sclerosis (MS) plaques by using diffusional kurtosis imaging (DKI) to …