Phosphorylation of cAMP response element-binding protein in hippocampal neurons as a protective response after exposure to glutamate in vitro and ischemia in vivo

…, K Kitagawa, K Kuwabara, K Takasawa… - Journal of …, 2001 - Soc Neuroscience
Although accumulating evidence indicates that cAMP response element-binding protein (CREB)
phosphorylation mediates not only synaptic plasticity but also survival of certain neurons…

Correlation of angiographic circulation time and cerebrovascular reserve by acetazolamide-challenged single photon emission CT

…, T Uematsu, K Takasawa… - American journal …, 2004 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Although cerebral circulation time (CCT) is one of the main
parameters in cerebral blood flow measurements, its clinical significance is controversial. …

Differential Akt phosphorylation at Ser473 and Thr308 in cultured neurons after exposure to glutamate in rats

K Kitagawa, K Takasawa, K Kuwabara, T Sasaki… - Neuroscience …, 2002 - Elsevier
Akt kinase is involved in growth factor-mediated neuronal protection. In the present study,
we found in cultured neurons exposed to glutamate, that phosphorylation at Ser473 was …

Preparation of Mutants Resistant to Catabolite Repression of Trichoderma reesei

…, Y Shinsha, K Takayama, S Takasawa - Agricultural and …, 1985 - academic.oup.com
The development of agar plate screening techniques has allowed the isolation of mutants of
Trichoderma reesei capable of synthesizing cellulase under the conditions of a high …

Identical NR5A1 Missense Mutations in Two Unrelated 46,XX Individuals with Testicular Tissues

M Igarashi, K Takasawa, A Hakoda, J Kanno… - Human …, 2017 - Wiley Online Library
The role of monogenic mutations in the development of 46,XX testicular/ovotesticular disorders
of sex development (DSD) remains speculative. Although mutations in NR5A1 are known …

Fortimicins A and B, new aminoglycoside antibiotics I. Producing organism, fermentation and biological properties of fortimicins

…, K TAKAYAMA, RYO OKACHI, S TAKASAWA… - The Journal of …, 1977 - jstage.jst.go.jp
A culture of Micromonospora species MK-70 was found to produce two new antibiotics,
fortimicins A and B. Antibacterial and paper chromatographic data on an eluate from IRC-50 …

[HTML][HTML] Differences in clinical characteristics of cervical spine injuries in older adults by external causes: a multicenter study of 1512 cases

…, H Tominaga, H Tokumoto, Y Iizuka, E Takasawa… - Scientific reports, 2022 - nature.com
Although traumatic cervical spine injuries in older adults are commonly caused by minor
traumas, such as ground-level falls, their prognosis is often unfavorable. Studies examining the …

Epidemiology of cervical fracture/cervical spinal cord injury and changes in surgical treatment modalities in elderly individuals during a 10-year period: a nationwide …

…, K Kakutani, Y Iizuka, E Takasawa… - Global spine …, 2023 - journals.sagepub.com
Study Design Retrospective multicenter study Objectives To investigate changes over a 10-years
period in the profile of cervical spine and spinal cord injuries among the elderly in …

Prognosis of cervical diffuse idiopathic skeletal hyperostosis-related spine injuries in elderly patients: analyses of both fracture and spinal cord injury without fracture

…, Y Kakiuchi, Y Iizuka, E Takasawa… - Global Spine …, 2023 - journals.sagepub.com
Study Design Retrospective multicenter study. Objective The purpose of this study was to
compare the prognosis of elderly patients with injuries related to cervical diffuse idiopathic …

[HTML][HTML] A multicenter study of 1-year mortality and walking capacity after spinal fusion surgery for cervical fracture in elderly patients

…, H Tokumoto, T Kaito, Y Iizuka, E Takasawa… - BMC Musculoskeletal …, 2022 - Springer
Background The 1-year mortality and functional prognoses of patients who received surgery
for cervical trauma in the elderly remains unclear. The aim of this study is to investigate the …