Histone Methylation and STAT‐3 Differentially Regulate Interleukin‐6–Induced Matrix Metalloproteinase Gene Activation in Rheumatoid Arthritis Synovial Fibroblasts
…, Y Aizaki, K Sato, K Yokota, K Fujimoto… - Arthritis & …, 2016 - Wiley Online Library
Objective Synovial fibroblasts (SFs) produce matrix‐degrading enzymes that cause joint
destruction in rheumatoid arthritis (RA). Epigenetic mechanisms play a pivotal role in …
destruction in rheumatoid arthritis (RA). Epigenetic mechanisms play a pivotal role in …
Programmed cell death during amphibian metamorphosis
K Nakajima, K Fujimoto, Y Yaoita - Seminars in cell & developmental …, 2005 - Elsevier
The death of different types of cells occurs in regressing or remodeling organs to transform
from a tadpole to a frog in both temporally and spatially regulated manners during amphibian …
from a tadpole to a frog in both temporally and spatially regulated manners during amphibian …
[HTML][HTML] Thyroid hormone receptor actions on transcription in amphibia: The roles of histone modification and chromatin disruption
Thyroid hormone (T3) plays diverse roles in adult organ function and during vertebrate
development. The most important stage of mammalian development affected by T3 is the …
development. The most important stage of mammalian development affected by T3 is the …
Dysembryoplastic neuroepithelial tumor of the cerebellum and brainstem: case report
K Fujimoto, H Ohnishi, M Tsujimoto, T Hoshida… - Journal of …, 2000 - thejns.org
✓ The authors present a case in which dysembryoplastic neuroepithelial tumors (DNETs)
occurred in the cerebellum and brainstem of a 44-year-old woman. A magnetic resonance …
occurred in the cerebellum and brainstem of a 44-year-old woman. A magnetic resonance …
Effect of carotid artery stenting on ocular circulation and chronic ocular ischemic syndrome
…, T Sakaki, H Iwahashi, K Fujimoto… - Cerebrovascular …, 2006 - karger.com
Background: The authors evaluated the effect of carotid artery stenting (CAS) on ocular
circulation and chronic ocular ischemic syndrome. Methods: We examined 38 patients with …
circulation and chronic ocular ischemic syndrome. Methods: We examined 38 patients with …
[HTML][HTML] The development of the adult intestinal stem cells: Insights from studies on thyroid hormone-dependent amphibian metamorphosis
YB Shi, T Hasebe, L Fu, K Fujimoto, A Ishizuya-Oka - Cell & bioscience, 2011 - Springer
Adult organ-specific stem cells are essential for organ homeostasis and repair in adult
vertebrates. The intestine is one of the best-studied organs in this regard. The intestinal epithelium …
vertebrates. The intestine is one of the best-studied organs in this regard. The intestinal epithelium …
Germinoma causing wallerian degeneration: case report and review of the literature
K Nagata, Y Nikaido, T Yuasa, K Fujimoto, YJ Kim… - Journal of …, 1998 - thejns.org
✓ Germinomas occurring in the thalamus and basal ganglia sometimes cause atrophy of the
cerebral hemisphere on the affected side. The authors present the case of a 12-year-old girl …
cerebral hemisphere on the affected side. The authors present the case of a 12-year-old girl …
Molecular and genetic studies suggest that thyroid hormone receptor is both necessary and sufficient to mediate the developmental effects of thyroid hormone
Thyroid hormone (TH) affects diverse biological processes and can exert its effects through
both gene regulation via binding the nuclear TH receptors (TRs) and non-genomic actions …
both gene regulation via binding the nuclear TH receptors (TRs) and non-genomic actions …
Liganded thyroid hormone receptor induces nucleosome removal and histone modifications to activate transcription during larval intestinal cell death and adult stem …
K Matsuura, K Fujimoto, L Fu, YB Shi - Endocrinology, 2012 - academic.oup.com
Thyroid hormone (T 3 ) plays an important role in regulating multiple cellular and metabolic
processes, including cell proliferation, cell death, and energy metabolism, in vertebrates. …
processes, including cell proliferation, cell death, and energy metabolism, in vertebrates. …
Thyroid Hormone-Induced Activation of Notch Signaling is Required for Adult Intestinal Stem Cell Development During Xenopus Laevis Metamorphosis
T Hasebe, K Fujimoto, M Kajita, L Fu, YB Shi… - Stem Cells, 2017 - academic.oup.com
In Xenopus laevis intestine during metamorphosis, the larval epithelial cells are removed by
apoptosis, and the adult epithelial stem (AE) cells appear concomitantly. They proliferate …
apoptosis, and the adult epithelial stem (AE) cells appear concomitantly. They proliferate …