Histone Methylation and STAT‐3 Differentially Regulate Interleukin‐6–Induced Matrix Metalloproteinase Gene Activation in Rheumatoid Arthritis Synovial Fibroblasts

…, Y Aizaki, K Sato, K Yokota, K Fujimoto… - Arthritis & …, 2016 - Wiley Online Library
Objective Synovial fibroblasts (SFs) produce matrix‐degrading enzymes that cause joint
destruction in rheumatoid arthritis (RA). Epigenetic mechanisms play a pivotal role in …

Programmed cell death during amphibian metamorphosis

K Nakajima, K Fujimoto, Y Yaoita - Seminars in cell & developmental …, 2005 - Elsevier
The death of different types of cells occurs in regressing or remodeling organs to transform
from a tadpole to a frog in both temporally and spatially regulated manners during amphibian …

[HTML][HTML] Thyroid hormone receptor actions on transcription in amphibia: The roles of histone modification and chromatin disruption

YB Shi, K Matsuura, K Fujimoto, L Wen, L Fu - Cell & bioscience, 2012 - Springer
Thyroid hormone (T3) plays diverse roles in adult organ function and during vertebrate
development. The most important stage of mammalian development affected by T3 is the …

Dysembryoplastic neuroepithelial tumor of the cerebellum and brainstem: case report

K Fujimoto, H Ohnishi, M Tsujimoto, T Hoshida… - Journal of …, 2000 - thejns.org
✓ The authors present a case in which dysembryoplastic neuroepithelial tumors (DNETs)
occurred in the cerebellum and brainstem of a 44-year-old woman. A magnetic resonance …

Effect of carotid artery stenting on ocular circulation and chronic ocular ischemic syndrome

…, T Sakaki, H Iwahashi, K Fujimoto… - Cerebrovascular …, 2006 - karger.com
Background: The authors evaluated the effect of carotid artery stenting (CAS) on ocular
circulation and chronic ocular ischemic syndrome. Methods: We examined 38 patients with …

[HTML][HTML] The development of the adult intestinal stem cells: Insights from studies on thyroid hormone-dependent amphibian metamorphosis

YB Shi, T Hasebe, L Fu, K Fujimoto, A Ishizuya-Oka - Cell & bioscience, 2011 - Springer
Adult organ-specific stem cells are essential for organ homeostasis and repair in adult
vertebrates. The intestine is one of the best-studied organs in this regard. The intestinal epithelium …

Germinoma causing wallerian degeneration: case report and review of the literature

K Nagata, Y Nikaido, T Yuasa, K Fujimoto, YJ Kim… - Journal of …, 1998 - thejns.org
✓ Germinomas occurring in the thalamus and basal ganglia sometimes cause atrophy of the
cerebral hemisphere on the affected side. The authors present the case of a 12-year-old girl …

Molecular and genetic studies suggest that thyroid hormone receptor is both necessary and sufficient to mediate the developmental effects of thyroid hormone

B Das, H Matsuda, K Fujimoto, G Sun… - General and …, 2010 - Elsevier
Thyroid hormone (TH) affects diverse biological processes and can exert its effects through
both gene regulation via binding the nuclear TH receptors (TRs) and non-genomic actions …

Liganded thyroid hormone receptor induces nucleosome removal and histone modifications to activate transcription during larval intestinal cell death and adult stem …

K Matsuura, K Fujimoto, L Fu, YB Shi - Endocrinology, 2012 - academic.oup.com
Thyroid hormone (T 3 ) plays an important role in regulating multiple cellular and metabolic
processes, including cell proliferation, cell death, and energy metabolism, in vertebrates. …

Thyroid Hormone-Induced Activation of Notch Signaling is Required for Adult Intestinal Stem Cell Development During Xenopus Laevis Metamorphosis

T Hasebe, K Fujimoto, M Kajita, L Fu, YB Shi… - Stem Cells, 2017 - academic.oup.com
In Xenopus laevis intestine during metamorphosis, the larval epithelial cells are removed by
apoptosis, and the adult epithelial stem (AE) cells appear concomitantly. They proliferate …