Palladium-catalyzed cross-coupling reaction of bis (pinacolato) diboron with 1-alkenyl halides or triflates: convenient synthesis of unsymmetrical 1, 3-dienes via the …

J Takagi, K Takahashi, T Ishiyama… - Journal of the American …, 2002 - ACS Publications
The synthesis of 1-alkenylboronic acid pinacol esters via a palladium-catalyzed cross-coupling
reaction of bis(pinacolato)diboron (pin 2 B 2 , pin = Me 4 C 2 O 2 ) with 1-alkenyl halides …

A borylcopper species generated from bis (pinacolato) diboron and its additions to α, β-unsaturated carbonyl compounds and terminal alkynes

K Takahashi, T Ishiyama, N Miyaura - Journal of Organometallic Chemistry, 2001 - Elsevier
The addition of bis(pinacolato)diboron [(Me 4 C 2 O 2 )B–B(O 2 C 2 Me 4 )] to α,β-unsaturated
carbonyl compounds giving β-boryl carbonyl compounds and the addition to terminal …

Addition and coupling reactions of bis (pinacolato) diboron mediated by CuCl in the presence of potassium acetate

K Takahashi, T Ishiyama, N Miyaura - Chemistry Letters, 2000 - academic.oup.com
The addition of bis(pinacolato)diboron [(Me 4 C 2 O 2 )BB(O 2 C 2 Me 4 )] to α,β-unsaturated
ketones, esters, nitriles, or terminal alkynes and the coupling with allyl chlorides were …

Glutamate transporter EAAT2: regulation, function, and potential as a therapeutic target for neurological and psychiatric disease

K Takahashi, JB Foster, CLG Lin - Cellular and Molecular Life Sciences, 2015 - Springer
Glutamate is the predominant excitatory neurotransmitter in the central nervous system.
Excitatory amino acid transporter 2 (EAAT2) is primarily responsible for clearance of extracellular …

Small-molecule activator of glutamate transporter EAAT2 translation provides neuroprotection

Q Kong, LC Chang, K Takahashi, Q Liu… - The Journal of …, 2014 - Am Soc Clin Investig
Glial glutamate transporter EAAT2 plays a major role in glutamate clearance in synaptic clefts.
Several lines of evidence indicate that strategies designed to increase EAAT2 expression …

Restored glial glutamate transporter EAAT2 function as a potential therapeutic approach for Alzheimer's disease

K Takahashi, Q Kong, Y Lin, N Stouffer… - Journal of experimental …, 2015 - rupress.org
Glutamatergic systems play a critical role in cognitive functions and are known to be defective
in Alzheimer’s disease (AD) patients. Previous literature has indicated that glial glutamate …

Serial follow-up MR imaging after gamma knife radiosurgery for vestibular schwannoma

H Nakamura, H Jokura, K Takahashi… - American journal …, 2000 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Gamma knife radiosurgery has become an important
treatment option for vestibular schwannoma. The effect of treatment can be assessed only by …

Increased glial glutamate transporter EAAT2 expression reduces epileptogenic processes following pilocarpine-induced status epilepticus

Q Kong, K Takahashi, D Schulte, N Stouffer, Y Lin… - Neurobiology of …, 2012 - Elsevier
Several lines of evidence indicate that glutamate plays a crucial role in the initiation of seizures
and their propagation; abnormal glutamate release causes synchronous firing of large …

Ndrg2 promotes neurite outgrowth of NGF-differentiated PC12 cells

K Takahashi, M Yamada, H Ohata, K Honda… - Neuroscience …, 2005 - Elsevier
Ndrg2 is a member of the N-myc downstream-regulated genes. Thus far, two different
isoforms of rat Ndrg2 protein, Ndrg2S and Ndrg2L, have been identified. Recently, we have …

Synthesis of 1-Alkenylboronic Esters via Palladium-Catalyzed Cross-Coupling Reaction of Bis(pinacolato)diboron with 1-Alkenyl Halides and Triflates

K Takahashi, J Takagi, T Ishiyama… - Chemistry Letters, 2000 - academic.oup.com
The synthesis of 1-alkenylboronic acid pinacol esters via the palladium-catalyzed cross-coupling
reaction of 1-alkenyl halides or triflates with bis(pinacolato)diboron [(Me 4 C 2 O 2 )BB(…