[HTML][HTML] Global, regional, and national disease burden estimates of acute lower respiratory infections due to respiratory syncytial virus in children younger than 5 years …
Background Respiratory syncytial virus (RSV) is the most common cause of acute lower
respiratory infection in young children. We previously estimated that in 2015, 33·1 million …
respiratory infection in young children. We previously estimated that in 2015, 33·1 million …
[HTML][HTML] Complete genome sequence of the metabolically versatile photosynthetic bacterium Rhodopseudomonas palustris
Rhodopseudomonas palustris is among the most metabolically versatile bacteria known. It
uses light, inorganic compounds, or organic compounds, for energy. It acquires carbon from …
uses light, inorganic compounds, or organic compounds, for energy. It acquires carbon from …
Phosphorylation of tau by fyn: implications for Alzheimer's disease
…, JM Litersky, K Bhaskar, SM Fang, LH Do… - Journal of …, 2004 - Soc Neuroscience
… that 9G3 does not react to a … do not bear resemblance to the tyr18 area, it is unlikely that
9G3 might recognize a phosphotyrosine in human tau other than tyr18. However, our data does …
9G3 might recognize a phosphotyrosine in human tau other than tyr18. However, our data does …
Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation
…, R Collins, R Courtney, G Davies, G Delgado, LD Do… - Nature …, 2015 - nature.com
We carried out a trans-ancestry genome-wide association and replication study of blood
pressure phenotypes among up to 320,251 individuals of East Asian, European and South …
pressure phenotypes among up to 320,251 individuals of East Asian, European and South …
Topological control in heterometallic metal− organic frameworks by anion templating and metalloligand design
SR Halper, L Do, JR Stork… - Journal of the American …, 2006 - ACS Publications
… can template identical topologies in coordination solids. … coordinative ability of the anion
does not play a significant role … ); thus, no comments can be provided on their location in the …
does not play a significant role … ); thus, no comments can be provided on their location in the …
Limb and kidney defects in Lmx1b mutant mice suggest an involvement of LMX1B in human nail patella syndrome
…, H Kokubo, KC Oberg, CV Pepicelli, L Can… - Nature …, 1998 - nature.com
… The fact that we do not observe any limb or renal phenotype … LMX1B proteins from NPS
patients will be required to address … an important advance and will facilitate further investigations …
patients will be required to address … an important advance and will facilitate further investigations …
[HTML][HTML] The spliceosome: design principles of a dynamic RNP machine
MC Wahl, CL Will, R Lührmann - cell, 2009 - cell.com
Ribonucleoproteins (RNPs) mediate key cellular functions such as gene expression and its
regulation. Whereas most RNP enzymes are stable in composition and harbor preformed …
regulation. Whereas most RNP enzymes are stable in composition and harbor preformed …
Spliceosome structure and function
CL Will, R Lührmann - Cold Spring Harbor perspectives …, 2011 - cshperspectives.cshlp.org
… penta-snRNP can be chased into an active spliceosome without first undergoing disassembly
and then subsequent reassembly. Thus, the generation of an active spliceosome does not …
and then subsequent reassembly. Thus, the generation of an active spliceosome does not …
Protein–protein interactions and 5'-splice-site recognition in mammalian mRNA precursors
JD Kohtz, SF Jamison, CL Will, P Zuo, R Lührmann… - Nature, 1994 - nature.com
… Although our results do not exclude this, they do indicate that these domains can mediate
specific protein–protein interactions. We have shown that the RS domain of ASF/SF2 and a …
specific protein–protein interactions. We have shown that the RS domain of ASF/SF2 and a …
Spliceosomal UsnRNP biogenesis, structure and function
CL Will, R Lührmann - Current opinion in cell biology, 2001 - Elsevier
Significant advances have been made in elucidating the biogenesis pathway and three-dimensional
structure of the UsnRNPs, the building blocks of the spliceosome. U2 and U4/U6•…
structure of the UsnRNPs, the building blocks of the spliceosome. U2 and U4/U6•…