Brain metastasis frequently occurs in individuals with cancer and is often fatal. We used
multiphoton laser scanning microscopy to image the single steps of metastasis formation in real …

Chimeric antigen receptor T cells (CAR-T cells) have emerged as a powerful treatment option
for individuals with B cell malignancies but have yet to achieve success in treating acute …

The therapeutic success and widespread approval of genetically engineered T cells for a
variety of hematologic malignancies spurred the development of synthetic cell-based …

Glioblastoma is the most common malignant primary brain tumor and is associated with a
poor prognosis even after multimodal therapy. Chimeric antigen receptor (CAR) T cells have …

Infiltration of cancer cells into normal tissue is a hallmark of malignant gliomas and compromises
treatment options. A lack of appropriate models limits the study of this invasion in vivo, …

Millions of platelets are produced each hour by bone marrow (BM) megakaryocytes (MKs).
MKs extend transendothelial proplatelet (PP) extensions into BM sinusoids and shed new …

… Louisa von Baumgarten—No disclosures reported. … , Niklas Thon, Marion Subklewe, and
Louisa von Baumgarten. 2021. "CAR T-Cells for CNS Lymphoma: Driving into New Terrain?" …

Purpose: Bevacizumab targets VEGF-A and has proved beneficial in glioma patients, improving
clinical symptoms by the reduction of tumor edema. However, it remains controversial …

… per L or platelet count of <100 × 10 9 platelets per L); a cardiac ejection fraction of less
than 50% or uncontrolled arrhythmias; a creatinine concentration of more than 1·5 mg/dL or a …

Background and Purpose— Vertebral artery hypoplasia (VAH) is supposed to be a risk factor
for posterior circulation ischemia (PCI), particularly in the territory of the posterior inferior …