User profiles for L.A. Mitchell

Leslie Mitchell

Postdoctoral Felllow, New York University
Verified email at nyumc.org
Cited by 6788

Claudins: control of barrier function and regulation in response to oxidant stress

CE Overgaard, BL Daugherty, LA Mitchell… - Antioxidants & redox …, 2011 - liebertpub.com
Claudins are a family of nearly two dozen transmembrane proteins that are a key part of the
tight junction barrier that regulates solute movement across polarized epithelia. Claudin …

CT, MRI, PET, PET/CT, and ultrasound in the evaluation of obstetric and gynecologic patients

…, DA Prager, TF Murphy, BD Berkey, LA Mitchell - Surgical Clinics of North …, 2008 - Elsevier
The role of imaging in obstetrics and gynecology has undergone a revolution over the past
few decades. Well-established methods such as endovaginal ultrasound have had a central …

Epileptology of the first-seizure presentation: a clinical, electroencephalographic, and magnetic resonance imaging study of 300 consecutive patients

MA King, MR Newton, GD Jackson, GJ Fitt, LA Mitchell… - The Lancet, 1998 - thelancet.com
… FRACR L Anne Mitchell L Anne Mitchell … Graeme Jackson, Greg Fitt, and Anne Mitchell
critically reviewed the MRI studies. Mervyn Silvapulle did the statistical analyses. All investigators …

Total synthesis of a functional designer eukaryotic chromosome

N Annaluru, H Muller, LA Mitchell, S Ramalingam… - science, 2014 - science.org
Rapid advances in DNA synthesis techniques have made it possible to engineer viruses,
biochemical pathways and assemble bacterial genomes. Here, we report the synthesis of a …

Temporal lobectomy: long-term seizure outcome, late recurrence and risks for seizure recurrence

AM McIntosh, RM Kalnins, LA Mitchell, GCA Fabinyi… - Brain, 2004 - academic.oup.com
There is little information available relevant to long-term seizure outcome after anterior temporal
lobectomy, particularly at extended postoperative periods. The aim of this study was an …

Design of a synthetic yeast genome

SM Richardson, LA Mitchell, G Stracquadanio, K Yang… - Science, 2017 - science.org
We describe complete design of a synthetic eukaryotic genome, Sc2.0, a highly modified
Saccharomyces cerevisiae genome reduced in size by nearly 8%, with 1.1 megabases of the …

[HTML][HTML] Temperature and the cold pressor test

LA Mitchell, RAR MacDonald, EE Brodie - The journal of pain, 2004 - Elsevier
As a method of experimental pain induction, the cold pressor test is thought to mimic the
effects of chronic conditions effectively. A survey of previous studies using the cold pressor, …

Synthetic genomes

W Zhang, LA Mitchell, JS Bader… - Annual review of …, 2020 - annualreviews.org
DNA synthesis technology has progressed to the point that it is now practical to synthesize
entire genomes. Quite a variety of methods have been developed, first to synthesize single …

DNA damage in human spermatozoa is highly correlated with the efficiency of chromatin remodeling and the formation of 8-hydroxy-2′-deoxyguanosine, a marker of …

GN De Iuliis, LK Thomson, LA Mitchell… - Biology of …, 2009 - academic.oup.com
DNA damage in human spermatozoa has been associated with a range of adverse clinical
outcomes, including infertility, abortion, and disease in the offspring. We have advanced a two…

Pulmonary and systemic immune response to inhaled multiwalled carbon nanotubes

LA Mitchell, J Gao, RV Wal, A Gigliotti… - Toxicological …, 2007 - academic.oup.com
Inhalation of multiwalled carbon nanotubes (MWCNTs) at particle concentrations ranging
from 0.3 to 5 mg/m 3 did not result in significant lung inflammation or tissue damage, but …