Purpose— Symptomatic intracranial hemorrhage (sICH) is the most feared complication of
intravenous thrombolytic therapy in acute ischemic stroke. Treatment of sICH is based on …

OBJECTIVE: Preexisting spinal arteriovenous malformation nomenclature can be confusing.
The aim of this article is to present a modified classification system for spinal arteriovenous …

BACKGROUND: The results of treatment of intracranial dural arteriovenous fistulas (DAVFs)
since Onyx became available as an embolic agent at their institution is reported. An …

Nonalcoholic fatty liver disease (NAFLD) clusters in families, but the only known common
genetic variants influencing risk are near PNPLA3. We sought to identify additional genetic …

Object. The authors prospectively compared a new technique of surgical microscope-based
indocyanine green (ICG) videoangiography with intraoperative or postoperative digital …

Background Standard therapy for glioblastoma includes surgery, radiotherapy, and
temozolomide. This Phase 3 trial evaluates the addition of an autologous tumor lysate-pulsed …

Genome-wide association studies have identified 32 loci influencing body mass index, but
this measure does not distinguish lean from fat mass. To identify adiposity loci, we meta-…

A decline in capillary density and blood flow with age is a major cause of mortality and morbidity.
Understanding why this occurs is key to future gains in human health. NAD precursors …

Background— Cardiac troponin I (cTnI) is a highly sensitive and specific marker for myocardial
injury that predicts outcomes in patients with acute coronary syndromes. Cardiovascular …

Glycoprotein adhesion receptors such as selectins contribute to tissue injury in stroke.
Ischemic neurons strongly expressed C1q, which may target them for complement-mediated …