Superparamagnetic iron oxide nanoparticles: diagnostic magnetic resonance imaging and potential therapeutic applications in neurooncology and central nervous …
…, B Hamilton, WD Rooney, LL Muldoon… - Journal of Cerebral …, 2010 - journals.sagepub.com
Superparamagnetic iron oxide nanoparticles have diverse diagnostic and potential
therapeutic applications in the central nervous system (CNS). They are useful as magnetic …
therapeutic applications in the central nervous system (CNS). They are useful as magnetic …
[PDF][PDF] Chemotherapy delivery issues in central nervous system malignancy: a reality check
LL Muldoon, C Soussain… - Journal of …, 2007 - oww-files-public.s3.amazonaws.com
Purpose This review assesses the current state of knowledge regarding preclinical and
clinical pharmacology for brain tumor chemotherapy and evaluates relevant brain tumor …
clinical pharmacology for brain tumor chemotherapy and evaluates relevant brain tumor …
Immunologic privilege in the central nervous system and the blood–brain barrier
LL Muldoon, JI Alvarez, DJ Begley… - Journal of Cerebral …, 2013 - journals.sagepub.com
The brain is in many ways an immunologically and pharmacologically privileged site. The
blood–brain barrier (BBB) of the cerebrovascular endothelium and its participation in the …
blood–brain barrier (BBB) of the cerebrovascular endothelium and its participation in the …
Safety and efficacy of a multicenter study using intraarterial chemotherapy in conjunction with osmotic opening of the blood‐brain barrier for the treatment of patients …
…, DF Kraemer, D Fortin, R Nixon, LL Muldoon… - Cancer, 2000 - Wiley Online Library
BACKGROUND The aim of this study was to determine the safety and efficacy of intraarterial
chemotherapy with osmotic opening of the blood‐brain barrier (BBB) for the treatment of …
chemotherapy with osmotic opening of the blood‐brain barrier (BBB) for the treatment of …
[HTML][HTML] Current and potential imaging applications of ferumoxytol for magnetic resonance imaging
…, BE Hamilton, X Li, HL McConnell, LL Muldoon… - Kidney international, 2017 - Elsevier
Contrast-enhanced magnetic resonance imaging is a commonly used diagnostic tool.
Compared with standard gadolinium-based contrast agents, ferumoxytol (Feraheme, AMAG …
Compared with standard gadolinium-based contrast agents, ferumoxytol (Feraheme, AMAG …
Protection against cisplatin-induced toxicities by N-acetylcysteine and sodium thiosulfate as assessed at the molecular, cellular, and in vivo levels
DT Dickey, YJ Wu, LL Muldoon, EA Neuwelt - Journal of Pharmacology and …, 2005 - ASPET
Cisplatin (CDDP) is a common, highly toxic chemotherapeutic agent. This study investigates
chemoprotective effects of N-acetylcysteine (NAC) and sodium thiosulfate (STS) on in vitro …
chemoprotective effects of N-acetylcysteine (NAC) and sodium thiosulfate (STS) on in vitro …
Imaging of iron oxide nanoparticles by MR and light microscopy in patients with malignant brain tumours
…, P Varallyay, AG Bago, LL Muldoon… - Neuropathology and …, 2004 - Wiley Online Library
Objective: Ferumoxtran‐10 (Combidex ® ), a dextran‐coated iron oxide nanoparticle, provides
enhancement of intracranial tumours by magnetic resonance (MR) for more than 24 h and …
enhancement of intracranial tumours by magnetic resonance (MR) for more than 24 h and …
The chemoprotective agent N-acetylcysteine blocks cisplatin-induced apoptosis through caspase signaling pathway
YJ Wu, LL Muldoon, EA Neuwelt - Journal of Pharmacology and …, 2005 - ASPET
Thiols such as N-acetylcysteine (NAC) are increasingly used in clinical trials of platinum
chemotherapy as chemoprotectants. NAC can prevent cisdiamminedichloroplatinum (cisplatin)-…
chemotherapy as chemoprotectants. NAC can prevent cisdiamminedichloroplatinum (cisplatin)-…
Imaging, distribution, and toxicity of superparamagnetic iron oxide magnetic resonance nanoparticles in the rat brain and intracerebral tumor
LL Muldoon, M Sàndor, KE Pinkston, EA Neuwelt - Neurosurgery, 2005 - journals.lww.com
OBJECTIVE: Superparamagnetic iron oxide nanoparticle magnetic resonance imaging (MRI)
contrast agents are gaining use in the central nervous system. The purpose of this study …
contrast agents are gaining use in the central nervous system. The purpose of this study …
Pseudoprogression of glioblastoma after chemo-and radiation therapy: diagnosis by using dynamic susceptibility-weighted contrast-enhanced perfusion MR imaging …
S Gahramanov, LL Muldoon, CG Varallyay, X Li… - Radiology, 2013 - pubs.rsna.org
Purpose To compare gadoteridol and ferumoxytol for measurement of relative cerebral blood
volume (rCBV) in patients with glioblastoma multiforme (GBM) who showed progressive …
volume (rCBV) in patients with glioblastoma multiforme (GBM) who showed progressive …