BACKGROUND AND PURPOSE: A technique of segmenting total gray matter (GM) and total
white matter (WM) in human brain is now available. We investigated the effects of age and …

PURPOSE: To prospectively determine hemodynamic changes in the normal-appearing
white matter (NAWM) of patients with relapsing-remitting multiple sclerosis (RR-MS) by using …

BACKGROUND AND PURPOSE: Although mild or moderate traumatic brain injury (TBI) is
known to cause persistent neurologic sequelae, the underlying structural changes remain …

Object. This study was conducted to determine whether proton magnetic resonance
spectroscopy (MRS) is a sensitive method for detecting diffuse axonal injury, which is a primary …

BACKGROUND AND PURPOSE: Perfusion measurement in multiple sclerosis (MS) may
cast light on the disease pathogenesis and lesion development since vascular pathology is …

PURPOSE: To determine annual rates of volumetric changes in the whole-brain parenchyma
of patients with relapsing-remitting and secondary progressive multiple sclerosis (MS) and …

BACKGROUND AND PURPOSE: The magnetization transfer ratio (MTR) is a sensitive and
quantitative identifier of underlying structural changes in the brain. We quantitatively …

BACKGROUND AND PURPOSE: Contrast enhancement on MR images of patients with
multiple sclerosis (MS) is known to be associated with abnormalities of the blood-brain barrier (…

BACKGROUND AND PURPOSE: Recent animal and human studies have shown an
increased frequency of enlarged, high-convexity Virchow-Robin spaces (VRS) in several …

Article abstract Scores on the University of Pennsylvania Smell Identification Test (UPSIT),
as well as the numbers of MRI-determined plaques within the inferior frontal and temporal …