Optimising the conduct of clinical trials for diffuse intrinsic pontine glioma involves use of
consistent, objective disease assessments and standardised response criteria. The Response …

Purpose: To determine the values of iron accumulation in the basal ganglia of healthy
volunteers of different ages with R2* and raw signal intensity measurements from T1-weighted …

Objective Cerebral amyloid angiopathy–related inflammation (CAA‐ri) is characterized by
vasogenic edema and multiple cortical/subcortical microbleeds, sharing several aspects with …

Neurodegeneration with brain iron accumulation (NBIA) comprises a clinically and
genetically heterogeneous group of disorders with progressive extrapyramidal signs and …

Chiari malformations 1, 2, 3 represent different degrees of herniation of posterior fossa
content into the cervical canal (Chiari 1 and 2), or through an upper-cervical meningocele (Chiari …

Background: The safety and efficacy of the oral iron‐chelating agent deferiprone on magnetic
resonance pallida iron concentration and on clinical status were investigated in 10 patients …

Aicardi-Goutières syndrome (AGS) is a genetically determined early onset encephalopathy
characterized by cerebral calcification, leukodystrophy, and increased expression of …

Hereditary spastic paraplegias are a heterogeneous group of neurodegenerative disorders,
clinically classified in pure and complex forms. Genetically, more than 70 different forms of …

Purpose. Periventricular nodular heterotopia (PNH) is among the most common malformations
of cortical development, and affected patients are frequently characterized by focal drug‐…

We report the results of deep brain stimulation (DBS) of the globus pallidus internus (GPi) in
12 patients with childhood‐onset generalized dystonia refractory to medication, including 3 …