CNS metastases are the most common cause of malignant brain tumours in adults. Historically,
patients with brain metastases have been excluded from most clinical trials, but their …

Question Should patients with newly-diagnosed metastatic brain tumors undergo stereotactic
radiosurgery (SRS) compared with other treatment modalities? Target population These …

… of survival, however, class II evidence suggests that survival is not decreased when WBRT
is not given as initial therapy (for details, refer to the guideline paper in this series by Linskey …

… Joanna M Zakrzewska professor of pain medicine in relation to oral medicine1, Mark E
Linskey … 61 Linskey ME, Ratanatharathorn V, Penagaricano J. A prospective cohort study of …

Should whole brain radiation therapy (WBRT) be used as the sole therapy in patients with
newly-diagnosed, surgically accessible, single brain metastases, compared with WBRT plus …

Question Do steroids improve neurologic symptoms in patients with metastatic brain tumors
compared to no treatment? If steroids are given, what dose should be used? Comparisons …

… Linskey ME, Sekhar LN. Cavernous sinus hemangiomas: a series, a review, and a …
Comment on Linskey ME, Sekhar LN: cavernous sinus hemangiomas: a series, a review, and a …

… Linskey and Sekhar thoroughly evaluate and plan surgery for their three patients with
cavernous hemangiomas and present an excellent study of planning and executing surgery for …

Target population This recommendation applies to adults with newly diagnosed brain
metastases; however, the recommendation below does not apply to the exquisitely …

… Linskey ME: Stereotactic radiosurgery versus stereotactic radiotherapy for patients with
vestibular schwannomas: a Leksell Gamma Knife Society 2000 debate. J Neurosurg 93 (3 Suppl)…